A challenge to "homochirality in sugar metabolism"Analysis of L-glucose catabolic pathway
A challenge to "homochirality in sugar metabolism"Analysis of L-glucose catabolic pathway
批准号:
21380054
负责人:
NAKAMURA Akira
金额:
$11.98万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2012
中文摘要
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英文摘要
Most organisms on the Earth can utilize D-glucose as carbon and energy sources, but utilization of its enantiomer, L-glucose, was not reported so far. Therefore it is generally recognized that there is a homochirality issue in sugar utilization. In this study we have analyzed, at enzyme and genetic levels, an L-glucose catabolic pathway in Paracoccus sp. 43P, an L-glucose utilizing bacterium isolated from soil, and succeeded in its elucidation for the first time. The results may contribute further understanding of homochirality issues of living organisms.
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L-glucose dehydrogenase, the first enzyme for L-glucose metabolism in Paracoccus sn.43P.
L-葡萄糖脱氢酶,副球菌 sn.43P 中第一个进行 L-葡萄糖代谢的酶。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[T.Shimizu, N.Takaya, A.Nakamura]
通讯作者:
A.Nakamura
L-グルコース代謝機構の発見
L-葡萄糖代谢机制的发现
DOI:
--
发表时间:
2013
期刊:
バイオサイエンスとインダストリー
影响因子:
--
作者:
[白石宗, 冨田理, 田中尚人, 吹谷智, 森田直樹, 横田伸一, 岡田早苗, 横田篤, 鈴木健策, 西村あおい・鈴木伊作・江沢辰広・斎藤勝晴, 中村 顕]
通讯作者:
中村 顕
Paracoccus属細菌43P株のL-グルコース代謝経路
副球菌菌株43P的L-葡萄糖代谢途径
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[清水哲, 高谷直樹, 中村顕]
通讯作者:
中村顕
L-グルコース代謝の初発酵素L-GDHの結晶構造解析
L-葡萄糖代谢起始酶L-GDH的晶体结构分析
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[深野和紘, 清水哲, 佐々木康幸, 中村顕, 矢嶋俊介]
通讯作者:
矢嶋俊介
DOI:
10.1074/jbc.m112.403055
发表时间:
2012-11-23
期刊:
JOURNAL OF BIOLOGICAL CHEMISTRY
影响因子:
4.8
作者:
[Shimizu, Tetsu, Takaya, Naoki, Nakamura, Akira]
通讯作者:
Nakamura, Akira
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Studies on Characteristic Properties of Covalently Bonded Transition Metal Complexes
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