Studies on how cytoskeleton-related molecules regulate neuronal migration, the brain formation as well as the maturation.
Studies on how cytoskeleton-related molecules regulate neuronal migration, the brain formation as well as the maturation.
批准号:
21390052
负责人:
SATO Makoto
金额:
$12.15万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
It has been demonstrated that LL5beta and FILIP bind to filamin A, one of well-known actin-binding molecules, and exert their important activities over cell migration, especially radial migration that is essential for the neocortex development. In the present study, we further pursued the possible roles of LL5beta and FILIP in the adult brain and found that LL5beta plays an important role for spine development and that FILIP for synaptic transmission through modulating the morphology of spines and subcellular localization of glutamate receptors. In addition, we observed that some actin-binding molecules, other than filamin A, are involved in their activities.
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Phosphatidylinositol (3,4,5)-triphosphate associated factor LL5βregulates morphology and maturation of dendritic spines
磷脂酰肌醇 (3,4,5)-三磷酸相关因子 LL5β 调节树突棘的形态和成熟
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Xie, M-J., Yagi, H., Iguchi, T., Sato, M.]
通讯作者:
M.
大脳皮質形成関連因子の神経回路形成における機能解析~トランスポゾンによる染色体遺伝子導入と遺伝子発現誘導系を用いたアプローチ-
神经回路形成中大脑皮层形成相关因素的功能分析 - 利用转座子和基因表达诱导系统的染色体基因导入方法 -
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[猪口徳一, 黒田一樹, 謝敏カク, 八木秀司, 佐藤真]
通讯作者:
佐藤真
福井大学での最近のデータ紹介
福井大学最新数据介绍
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Ushiki T, Iwata F, 藤宮峯子, 佐藤真]
通讯作者:
佐藤真
SNPアレイを用いた骨量との関連解析-ヒトゲノム、マウスモデル、ならびに発現解析を用いた骨粗鬆症疾患関連遺伝子の同定
使用SNP阵列进行骨量关联分析 - 使用人类基因组、小鼠模型和表达分析鉴定骨质疏松症相关基因
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[浦野友彦, 白木正孝,八木秀司, 佐藤真, 大内尉義, 井上聡]
通讯作者:
井上聡
LL5β regulates morphology and maturation of dendritic spines.
LL5β 调节树突棘的形态和成熟。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Xie, M-J., Iguchi, T.,Yagi, H., Shirao, T., Sato, M.]
通讯作者:
M.
共 39 条
Possible roles of microglia and the underlying mechanisms on the brain development
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批准号:25670091
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2013
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负责人:SATO Makoto
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Symbiotic and Supra-hegemonic International Order : Comprehensive Study of the English School of International Relations
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批准号:23530204
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2011
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负责人:SATO Makoto
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Experimental approach for direct transformation of GABAergic neurons
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批准号:23659092
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2011
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负责人:SATO Makoto
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Investigation of thin liquid film brake with measuring sound speed in the film
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批准号:22654048
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$0.55万
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财政年份:2010
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负责人:SATO Makoto
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依托单位:
Regulation of retinotopy by Wnt signaling in the higher order visual center
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批准号:22700333
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.58万
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财政年份:2010
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负责人:SATO Makoto
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A Study about Retired Farmer's Life and Labor in Rural Communities of Hokkaido
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批准号:21580276
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.33万
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财政年份:2009
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负责人:SATO Makoto
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依托单位:
A Human scale haptic VR environment with both hands multi-fingers manipulation
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批准号:20300044
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.23万
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财政年份:2008
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负责人:SATO Makoto
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依托单位:
Study for acceptance of Chinese characters in Ancient Japan
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批准号:20520565
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.25万
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财政年份:2008
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负责人:SATO Makoto
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依托单位:
Studies on how actins and microtubules are coordinated and its relevancy.
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批准号:19390048
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.31万
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财政年份:2007
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负责人:SATO Makoto
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依托单位:
Regional Cooperation and International Migration in and around Japan and South Africa : Prospect of Human Security
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批准号:19310160
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.9万
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财政年份:2007
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负责人:SATO Makoto
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依托单位:
Elucidation of mechanisms underlying formation of laminar structures of the brain using Drosophila visual system
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批准号:19700316
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.42万
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财政年份:2007
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负责人:SATO Makoto
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依托单位:
Studies on molecular mechanisms that regulate Filamin A subcellular localization and resultant changes in cell morphology.
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批准号:17390050
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.41万
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财政年份:2005
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负责人:SATO Makoto
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依托单位:
Cell biological studies on the mechanisms of directed migration toward the pial surface from the cortical ventricular zone
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批准号:15390054
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.92万
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财政年份:2003
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负责人:SATO Makoto
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依托单位:
RESEARCH AND SURVEY ON BSE PROBLEMS AND USAGE OF LOCALLY-PRODUCED FOODS IN SCHOOL LUNCHES
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批准号:15500562
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2003
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负责人:SATO Makoto
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依托单位:
Development of Human Scale Virtual Environment with a Haptic Display
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批准号:14350196
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.49万
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财政年份:2002
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负责人:SATO Makoto
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依托单位:
Management System of Agriculture-forestry Land and Regional Public Policy in the Age of Glolisation
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批准号:13460100
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.22万
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财政年份:2001
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负责人:SATO Makoto
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依托单位:
A Native imitative computer vision for a following generation human interface
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批准号:12650365
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.9万
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财政年份:2000
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负责人:SATO Makoto
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依托单位:
A novel mechanism that controls frequency and stability of lamellipodium formation
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批准号:12470002
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.13万
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财政年份:2000
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负责人:SATO Makoto
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依托单位:
Development Interface for creative design environment with haptic sensation
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批准号:11555099
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$6.66万
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财政年份:1999
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负责人:SATO Makoto
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依托单位:
Study on the historical landscape of ancient Japanese temples and manors
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批准号:11301011
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$22.54万
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财政年份:1999
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负责人:SATO Makoto
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依托单位:
海外基金