Analysis of benefits of dental pulp stem cells from permanent and milk teeth for the treatment of the intractable diseases and of their banking system.

根据细胞库技术的发展，我们建立了一个快速制备牙髓干细胞的系统，用于疾病区域的移植。此外，我们发现牙髓干细胞的无血清条件培养基（CM）用于治疗各种难治性疾病，包括脑梗死，严重骨缺损，脊髓损伤和暴发性肝功能衰竭的显着治疗益处。我们的研究表明，新开发的细胞库系统的显着优势和牙髓干细胞及其CM治疗多种难治性疾病的治疗效益。

According to the development of the cell banking technology, weestablished a system that allows to quickly prepare dental pulp stem cell for transplantation into the diseased area. Furthermore, we found remarkable therapeutic benefits of serum free conditioned media (CM) of the dental pulp stem cells for treatment of the various intractable diseases, including cerebral infraction, severe bone defects, spinal cordinjury and fulminant hepatic failure. Our study demonstrate a marked advantage of newly developed cell banking system and therapeutic benefits of the dental pulp stem cells and their CMs for treatment of the multiple refractory diseases.