The explore of the underlying molecular mechanisms of cardiac repair in cell sheet transplantation-mediated improvement of cardiac function
The explore of the underlying molecular mechanisms of cardiac repair in cell sheet transplantation-mediated improvement of cardiac function
批准号:
21790754
负责人:
MATSUURA Katsuhisa
金额:
$2.75万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
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英文摘要
When cardiac Sca-1 positive cells were isolated from the adult murine heart and were transplanted to infarcted heart as cell sheet, significant improvement of cardiac function was observed. Soluble form of VCAM-1 secreted from Sca-1 positive cells enhanced angiogenesis, cardioprotection, and migration of Sca-1 positive cells, which contributed to the improvement of cardiac function after cell sheet transplantation.
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Annual Review循環器(担当章:細胞移植によるパラクライン効果)
年度回顾心血管系统(章节:细胞移植的旁分泌作用)
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Yoshihisa A, Shimizu T, Owada T, Misaka T, Sato T, Suzuki S, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y, 松浦勝久]
通讯作者:
松浦勝久
Cell sheet transplantation promotes engraftment and cardiac differentiation of cardiac Sca-1(+) cells in the infarcted hear
细胞片移植促进梗死心脏中心脏 Sca-1( ) 细胞的植入和心脏分化
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[義久精臣, 松浦勝久]
通讯作者:
松浦勝久
血管・心筋の再生治療
血管/心肌再生治疗
DOI:
--
发表时间:
2009
期刊:
治療学 43
影响因子:
--
作者:
[松浦勝久, 萩原誠久]
通讯作者:
萩原誠久
The importance of paracrine effects of cardiac progenitor cell sheet transplantation for cardiac repair
心脏祖细胞片移植的旁分泌作用对心脏修复的重要性
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Yamaoka-Tojo M, Kitasato L, Nemoto S, Wakaume K, Kameda R, Yoshida Y, Machida Y, Tojo T, Kasuda T, Izumi T, 松浦勝久]
通讯作者:
松浦勝久
DOI:
10.1172/jci37456
发表时间:
2009-08-01
期刊:
JOURNAL OF CLINICAL INVESTIGATION
影响因子:
15.9
作者:
[Matsuura, Katsuhisa, Honda, Atsushi, Komuro, Issei]
通讯作者:
Komuro, Issei
共 15 条
Identification of cardioprotective growth factor derived from bone marrow mononuclear cells
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批准号:19790543
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.28万
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财政年份:2007
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负责人:MATSUURA Katsuhisa
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依托单位:
海外基金