Development of newly-designed molecular targeted diagnostic PET study using system A amino acid tracer

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In order to overcome the drawback of false positive diagnosis at FDG-PET in the patients with inflammatory diseases, we have developed[N-methyl-^<11> C] MeAIB, an artificial system A amino acid PET tracer, confirmed its safety at animal and human study, established its sophisticated synthesis methods, and established its basic procedure at clinical oncologic human study. We have finished more than 200 cases of patients with various tumors including brain tumors, chest cancers, and prostate cancers, and MeAIB-PET has shown its valuable clinical role in the differential diagnosis between cancers and inflammatory diseases.