A combinatorial approach to creation of new epitopes with biological activity

创建具有生物活性的新表位的组合方法

• 批准号: LP0347149
• 负责人: Prof Istvan Toth
• 金额: $ 19.9万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2003
• 资助国家: 澳大利亚
• 起止时间: 2003-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0347149
• 关键词: combinatorial; approach; creation; new; epitopes

We aim to develop and extend the Mosaic technology patented by Proxima Concepts Ltd. as a new methodolgy for dynamic combinatorial chemistry and drug delivery. The technology relies on bringing chemical structures of interest in close proximity by presenting them on the surface of a micelle type structure. These structures will also be developed at a targeted drug delivery vehicle. The technology will impact on the areas of drug discovery and drug delivery.

我们的目标是开发和扩展由Proxima Concepts Ltd.专利的Mosaic技术，作为动态组合化学和药物递送的新方法。 该技术依赖于通过将感兴趣的化学结构呈现在胶束型结构的表面上来使它们紧密接近。 这些结构也将被开发为靶向药物递送载体。 该技术将影响药物发现和药物输送领域。