Molecular mechanisms underlying reacquisition of proliferation competence during dedifferentiation of plant cells

对下胚轴脱分化温度敏感的拟南芥突变体的分子遗传学分析表明，前体mRNA剪接和rRNA生物合成因子的水平限制了植物细胞增殖的能力，在脱分化期间植物细胞增殖的重新获得涉及这些因子的增加，这种细胞增殖的控制是通过特异性NAC转录因子抑制增殖来调节的，细胞增殖所需的前体mRNA剪接能力依赖于细胞分裂素而变化。

The molecular genetic analysis of Arabidopsis mutants temperature-sensitive for hypocotyl dedifferentiation has shown that the levels of pre-mRNA splicing and rRNA biosynthesis factors limit the competence of plant cell proliferation, whose reacquisition during dedifferentiation involves increase of these factors, that this control of cell proliferation is meditated by the suppression of proliferation by a specific NAC transcription factor, and that the capacity of pre-mRNA splicing required for cell proliferation varies dependently on cytokinin.