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Molecular imaging of cholinergic system in the brain of autism: A positron emission tomography study.

Molecular imaging of cholinergic system in the brain of autism: A positron emission tomography study.
自闭症大脑胆碱能系统的分子成像:正电子发射断层扫描研究。
批准号:
22390221
负责人:
SUZUKI Katsuaki
金额:
$8.9万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
Aim of this studywas todetermine whether central acetylcholinesterase activity, a marker for the cholinergic system, is altered in subjects with autism spectrum disorder (ASD).Using positron emission tomography and a radiotracer , [11C]MP4A regional cerebrocortical acetylcholinesterase (AChE) activities wereestimated by reference tissue-based linear least-squaresanalysisin 20 adult subjects with ASD (14 male and 6 female; age range, 18-33 years) and 20 age-, sex-, and IQ-matched healthy controls. Both voxel-and region of interest-based analyses revealed significantly lower AChE activities in the bilateral fusiform gyri of subjects with ASD than in thoseof controls (P
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【多分野連携と子どものこころの解明への試み】自閉症の脳画像研究について
【多学科合作,阐释儿童心灵的尝试】关于自闭症脑影像研究
DOI: --
发表时间: 2010
期刊: 脳21
影响因子: --
作者: [鈴木勝昭, 中村和彦, 尾内康臣, 辻井正次, 森則夫]
通讯作者: 森則夫
DOI: 10.1001/archgenpsychiatry.2011.4
发表时间: 2011-03
期刊: Archives of general psychiatry
影响因子: --
作者: [Katsuaki Suzuki;G. Sugihara;Y. Ouchi;Kazuhiko Nakamura;M. Tsujii;M. Futatsubashi;Y. Iwata;K. Tsuchiya;Kaori Matsumoto;K. Takebayashi;Tomoyasu Wakuda;Y. Yoshihara;Shiro Suda;M. Kikuchi;N. Takei;Toshiro Sugiyama;T. Irie;N. Mori]
通讯作者: Katsuaki Suzuki;G. Sugihara;Y. Ouchi;Kazuhiko Nakamura;M. Tsujii;M. Futatsubashi;Y. Iwata;K. Tsuchiya;Kaori Matsumoto;K. Takebayashi;Tomoyasu Wakuda;Y. Yoshihara;Shiro Suda;M. Kikuchi;N. Takei;Toshiro Sugiyama;T. Irie;N. Mori
自閉症脳科学の最前線
自闭症神经科学的前沿
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Shimmura C, Suda S, Tsuchiya KJ, Hashimoto K, Ohno K, Matsuzaki H, Iwata K, Matsumoto K, Wakuda T, Kameno Y, Suzuki K, Tsujii M, Nakamura K, Takei N, Mori N, Miyake K, 鈴木勝昭]
通讯作者: 鈴木勝昭
バイオマーカーからみた自閉症スペクトラム障害
从生物标志物看出自闭症谱系障碍
DOI: --
发表时间: 2011
期刊: 小児の精神と神経
影响因子: --
作者: [Igarashi, T., Miyake, K., Asakawa, N., Shimada, T., Takahashi, H., 鈴木勝昭]
通讯作者: 鈴木勝昭
18
    Challenging Exploratory Research to Redefine Educational Technology from Design Research Perspective
    • 批准号:
      16K12793
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.08万
    • 财政年份:
      2016
    • 负责人:
      SUZUKI Katsuaki
    • 依托单位:
    Evaluation of a screening method based on the"T-cell dysfunction" hypothesis of major depressive disorder.
    • 批准号:
      23659561
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2011
    • 负责人:
      SUZUKI Katsuaki
    • 依托单位:
    Derivation of Aesthetic and Artistic Principles of Instructional Design
    • 批准号:
      22650206
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $1.8万
    • 财政年份:
      2010
    • 负责人:
      SUZUKI Katsuaki
    • 依托单位:
    Content Analysis and Development of Instructional Systems Graduate Courses as a Foundation for e-Learning
    • 批准号:
      15500632
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.05万
    • 财政年份:
      2003
    • 负责人:
      SUZUKI Katsuaki
    • 依托单位:
    海外基金