Investigation of the brain and cell injury responsible for depression with immune-challenged animal model
Investigation of the brain and cell injury responsible for depression with immune-challenged animal model
批准号:
22390226
负责人:
KANBA Shigenobu
金额:
$11.65万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
通过向小鼠全身注射细菌内毒素,我们产生了抑郁症的动物模型,其显示抑郁行为和室周器官周围区域的小胶质细胞活化。在另一项强迫游泳试验中,
英文摘要
By systemic injection of bacterial endotoxin into mice, we generated an animal model of depression which showed depressive behavior and microglial activation in the regions around the periventricular organs. In another experiment on forced swim test, some
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Controversies and New Treatment of Diabetes
糖尿病的争议和新治疗方法
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Kanba, S]
通讯作者:
S
DOI:
10.1016/j.schres.2011.07.020
发表时间:
2011-12
期刊:
Schizophrenia Research
影响因子:
4.5
作者:
[R. Tsuchimoto;S. Kanba;S. Hirano;N. Oribe;T. Ueno;Y. Hirano;I. Nakamura;Y. Oda;T. Miura;T. Onitsuka]
通讯作者:
R. Tsuchimoto;S. Kanba;S. Hirano;N. Oribe;T. Ueno;Y. Hirano;I. Nakamura;Y. Oda;T. Miura;T. Onitsuka
精神疾患における脳内炎症免疫機構の意義-統合失調症のミクログリア仮説
脑内炎症免疫机制在精神疾病中的意义——精神分裂症的小胶质细胞假说
DOI:
--
发表时间:
2011
期刊:
細胞工学
影响因子:
--
作者:
[加藤隆弘, 門司晃, 神庭重信]
通讯作者:
神庭重信
DOI:
10.1371/journal.pone.0039955
发表时间:
2012
期刊:
PloS one
影响因子:
3.7
作者:
[Oda Y, Onitsuka T, Tsuchimoto R, Hirano S, Oribe N, Ueno T, Hirano Y, Nakamura I, Miura T, Kanba S]
通讯作者:
Kanba S
DOI:
10.1007/s00213-011-2509-8
发表时间:
2012-04
期刊:
Psychopharmacology
影响因子:
3.4
作者:
[Motoki Watabe;Takahiro A. Kato;A. Monji;Hideki Horikawa;S. Kanba]
通讯作者:
Motoki Watabe;Takahiro A. Kato;A. Monji;Hideki Horikawa;S. Kanba
共 17 条
Disorder of reward circuit in bipolar disorders : integration of basic and clinical investigation
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批准号:19390306
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.73万
-
财政年份:2007
-
负责人:KANBA Shigenobu
-
依托单位:
Study on early environment-induced neuronal network which is involved in vulnerability to psychiatric disorders
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批准号:16390321
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.41万
-
财政年份:2004
-
负责人:KANBA Shigenobu
-
依托单位:
Molecular Research on Environmental Influence on Neuroplasticity and Neurogenesis
-
批准号:13470195
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.28万
-
财政年份:2001
-
负责人:KANBA Shigenobu
-
依托单位:
Effect of cytokines on the pathogenesis of mood disondens
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批准号:10470202
-
项目类别:Grant-in-Aid for Scientific Research (B).
-
资助金额:$2.94万
-
财政年份:1998
-
负责人:KANBA Shigenobu
-
依托单位:
A ROLE OF INTERLEUKIN-1 IN PATHOGENESIS OF MANIC-DEPRESSIVE-ILLNESS
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批准号:08457252
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$1.79万
-
财政年份:1996
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负责人:KANBA Shigenobu
-
依托单位:
海外基金