Sulcal neuroanatomy of human brain

人脑沟神经解剖学

• 批准号: 22390275
• 负责人: YOSHIMINE Toshiki
• 金额: $ 12.4万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22390275/
• 关键词: 脳溝; 神経接続性; 皮質脳波; コヒーレンス; ファイバートラッキング

We performed 3 dimensional neuroanatomical analyses of the central sulcus. The shape of the central sulcus was delineated from MR images using automatic sulcus detection software. Protrusion and surface area of the hand knob was significantly larger in the left side of the anterior wall of the central sulcus. The most medial portion of the hand area was stable in the axial MR images, which was meant to be useful as the origin of the local coordinate system. We applied this technique to intracranial electrode sheet manufacturing. We established a manufacturing method of automatic brain surface detection, mold design using 3D CAD, rapid manufacturing of the mold using a 3D printer, and manufacturing silicone electrode sheet fitting to individual brain surfaces. A high density 3D electrode array made using this method was used for an ALS patient in our clinical research of brain machine interfaces.

我们对中央沟进行了三维神经解剖学分析。使用自动沟检测软件从MR图像中勾画出中央沟的形状。中央沟前壁左侧的手钮突出和表面积明显较大。手的最内侧部分在轴向MR图像中是稳定的，这意味着它可以作为局部坐标系的原点。我们将此技术应用于颅内电极片的制造。建立了一种脑表面自动检测、3D CAD模具设计、3D打印机模具快速制造、脑表面硅胶电极片贴合的制造方法。本文将该方法制作的高密度三维电极阵列用于一名渐冻症患者的脑机接口临床研究。

项目成果

Motor Restoration based on the Brain Machine Interface using Brain Surface Elec- trodes: Real Time Robot Control and a Fully-implantable Wireless Sys- tem

基于使用脑表面电极的脑机接口的运动恢复：实时机器人控制和完全植入的无线系统

• DOI: 10.1163/156855311x614581
• 发表时间: 2011
• 期刊: Advanced Robotics
• 影响因子: 2
• 作者: Masayuki Hirata;Kojiro Matsushita;Takuhumi Yanagisawa;Tetsu Goto;Shayne Morris;Hiroshi Yokoi;Taka- fumi Suzuki;Tekeshi Yoshida;Fumi- hiro Sato;Osamu Sakura;Yasuyuki Kamitani;Toshiki Yoshimine
• 通讯作者: Toshiki Yoshimine

Current status and problems of neurosurgery in Asia

亚洲神经外科现状及问题

• 发表时间: 2013
• 作者: Takimoto A;他;岡田尚巳;Yoshimine T
• 通讯作者: Yoshimine T

Clinical BMI Roadmap in Japan

日本临床 BMI 路线图

• 发表时间: 2013
• 作者: P. Alberton;C. Popov;M. Pragert;J. Kohler;C. Shukunami;M. Schieker;and D. Docheva.;Yoshimine T
• 通讯作者: Yoshimine T

Clinical application of neuromagnetic recordings: from functional mapping to brain-machine interfaces

神经磁记录的临床应用：从功能映射到脑机接口

• 发表时间: 2013
• 作者: 斉藤克也;戸田正博;吉田一成;Hirata M
• 通讯作者: Hirata M

Connectivity changes in the epileptic brain

癫痫大脑的连接性变化

• 发表时间: 2012
• 作者: Esaki K;Terashima Y;Toda E;Yoshinaga S;Araki N;Matsushima K;Terasawa H;Yoshimine T
• 通讯作者: Yoshimine T