课题基金 / 基金详情

Application of focal brain cooling for intractable epilepsy

Application of focal brain cooling for intractable epilepsy
局灶性脑冷却在顽固性癫痫中的应用
批准号:
22390276
负责人:
SUZUKI Michiyasu
金额:
$12.4万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

项目摘要

项目成果

SUZUKI Michiyasu的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Safeness of focal brain cooling (FBC) for intractable epilepsy was verified. A rat epilepsy model was treated by the FBC. The optimal temperature to interrupt seizure without deteriorating neuronal function was 15 ℃. The FBC was applied at epilepsy surgery in human. Increased levels of glutamate and lactate reduced at 15 ℃. The FBC effectively inhibit neuronal excitotoxicity and anaerobic metabolism. Newly developed cooling device was successfully applied to cats and monkeys.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Insular psammomatous meningioma presenting intractable complex partial seizures.
岛叶砂粒细胞性脑膜瘤呈现顽固性复杂部分性癫痫发作。
DOI: --
发表时间: 2012
期刊: No Shinkei Geka
影响因子: --
作者: [Imoto H, Fujii M , Nomura S , Suzuki M, 他]
通讯作者:
Alterative treatment of intractable epilepsy with focal brain cooling -A review of our past studies
局灶性脑冷却替代治疗顽固性癫痫——我们过去研究的回顾
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Masami Fujii, Takao Inoue, Yeting He, Yuichi Maruta, Hirochika Imoto, Hiroyasu Koizumi, Sadahiro Nomura, Tatsuji Tokiwa, Satoshi Ishizuka, Takeshi Yamakawa, Toshitaka Yamakawa]
通讯作者: Toshitaka Yamakawa
DOI: 10.1016/j.clinph.2012.02.074
发表时间: 2012-09-01
期刊: CLINICAL NEUROPHYSIOLOGY
影响因子: 4.7
作者: [Kida, Hiroyuki, Fujii, Masami, Suzuki, Michiyasu]
通讯作者: Suzuki, Michiyasu
Inhibitory effects of focal brain cooling for motor cortical seizures in cats and nonhuman primates
局灶性脑冷却对猫和非人灵长类动物运动皮质癫痫发作的抑制作用
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Takao Inoue, Yeting He, Masami Fujii, Hiroshi Fujioka, Tatsuji Tokiwa, Hiroyuki Kida, Hirochika Imoto, Yuichi Maruta, Sadahiro Nomura, Takeshi Yamakawa, Michiyasu Suzuki]
通讯作者: Michiyasu Suzuki
38
    Protective effects of Focal brain cooling on cortical spreading depolarization in rats
    • 批准号:
      16K15646
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.16万
    • 财政年份:
      2016
    • 负责人:
      SUZUKI Michiyasu
    • 依托单位:
    Evaluation and control of epilepsy dynamics based on multimodal brain signals and thermal neuromodulation using focal brain cooling
    • 批准号:
      15H05719
    • 项目类别:
      Grant-in-Aid for Scientific Research (S)
    • 资助金额:
      $126.96万
    • 财政年份:
      2015
    • 负责人:
      SUZUKI Michiyasu
    • 依托单位:
    Experimental and theoretical investigations on effects of focal brain cooling on the generalized seizures
    • 批准号:
      25540136
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.41万
    • 财政年份:
      2013
    • 负责人:
      SUZUKI Michiyasu
    • 依托单位:
    Development of drug delivery system for central nervous system disease using with temperature control devise
    • 批准号:
      22659261
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $1.96万
    • 财政年份:
      2010
    • 负责人:
      SUZUKI Michiyasu
    • 依托单位:
    海外基金