Quantitative Diagnosis Method of Hepatic Disease based on AcousticCharacteristics of Tissues

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In this study, we developed a new quantitative diagnosis technique to estimate degree of fibrosis of the hepatitis liver using a model that expresses the amplitude distribution of the ultrasonic echo from a fibrotic liver tissue. In the model, the amplitude distribution is composed by three kinds of Rayleigh distribution corresponding to normal, fibrosis, nodule tissues. Using computer simulation, the tissue phantom, the clinical data, it was shown that the new quantitative technique is valid for the quantitative diagnosis of liver hepatitis.