Development of the measuring technique for ultrasonic attenuation distribution of tissues

组织超声衰减分布测量技术的发展

• 批准号: 07650471
• 负责人: HACHIYA Hiroyuki
• 金额: $ 1.28万
• 依托单位: CHIBA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07650471/
• 关键词: medical ultrasonics; living tissue; sound speed; sound attenuation; measurement method; 減速; 組織鑑別診断; 肝硬変; Bモード画像; 散乱体分布

The acoustic characteristics in biological tissues provide important diagnostic and treatment planning information. Conventional methods of sound speed determination generally require that transducers make physical contact with specimens in order to measure thickness and ultrasonic signal in the time domain. A method for determination of the sound speed and attenuation is proposed in which the sound travel time in the sample and the difference in total signal from the transducer to the rigid reflector due to the presence of the sample are estimated in the frequency domain and which does not require physical contact of ultrasonic probes to living or freshly excised tissue specimens. Using this method, the sound speeds and attenuation of human heart tissues are measured precisely. The speed and attenuation of sound in normal hearts varied minimally between individuals and was not related to body weight or age. Change of sound speed and attenuation of heart tissues was associated with histological change of a heart. Ultrasonic speed and attenuation measurements in tissues verified the method validity in medical application.

生物组织的声学特性为诊断和治疗计划提供了重要的信息。传统的声速测量方法一般要求换能器与试件进行物理接触，以便在时间域中测量厚度和超声信号。提出了一种确定声速和衰减的方法，该方法在频域中估计样品中的声波传播时间和由于样品的存在而从换能器到刚性反射器的总信号差，并且不需要超声探头与活的或新切除的组织样品进行物理接触。利用这种方法，可以精确地测量人体心脏组织的声速和衰减。正常心脏中声音的速度和衰减在个体之间差异很小，与体重或年龄无关。心脏组织声速和衰减的改变与心脏的组织学改变有关。通过对组织中超声速度和衰减的测量，验证了该方法在医学应用中的有效性。

项目成果

Editor : F,Punn H,Hachiya: "Ultrasonic Tissue Characterization" Springer-Verlag Tokyo, 10 (1996)

编辑：F，Punn H，Hachiya：“超声组织表征”Springer-Verlag Tokyo，10（1996）

Editor : F.Dunn: "Ultrasonic Tissue Characterization" Springer-Verleg Tokyo, 10 (1996)

编辑：F.Dunn：“超声组织表征”Springer-Verleg Tokyo，10 (1996)

蜂屋 弘之: "数10MHz帯パルス波を用いた心筋組織の音響特性評価" 超音波医学. 23・Sup2. 289 (1996)

Hiroyuki Hachiya：“使用数十MHz频带的脉冲波评估心肌组织的声学特性”超声医学23・Sup2。

蜂屋弘之: "超音波による生体の定量計測" 情報処理. 36. 1103-1109 (1995)

Hiroyuki Hachiya：“利用超声波对活体进行定量测量”信息处理 36. 1103-1109 (1995)。

H.Hachiya: "Ultrasonic Tissue Characterization" Editor-in-Chief : F.Dunn Springer. 63-72 (1996)

H.Hachiya：《超声组织表征》主编：F.Dunn Springer。