Estimation of the Scatterer Distribution for Quantitative Diagnosis using Ultrasonic Image

使用超声波图像进行定量诊断的散射体分布估计

• 批准号: 09650456
• 负责人: HACHIYA Hiroyuki
• 金额: $ 2.5万
• 依托单位: CHIBA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09650456/
• 关键词: medical ultrasonics; living tissue; quantitative diagnosis; liver cirrhosis; Rayleigh distribution; scatterer; 医用超音波; レイリー分布

In the B-mode image of the liver obtained by an ultrasonic imaging system, the speckled pattern changes with the progression of the disease such as liver cirrhosis. The human liver is composed of small hexagonal structures known as the liver lobules. We propose a modeling technique for the change of the scatterer distribution on liver tissue considering the liver lobule structure to obtain cirrhotic liver images of the continuous stage. The proposed modeling technique is valid for analyzing the relationship between the change of characteristics of biological tissue and change of B-mode image on the progression of liver cirrhosis. Then, we present the statistical characteristics of the echo envelope of the liver, and the technique to extract information of the scatterer distribution from the normal and cirrhotic liver images using constant false alarm rate (CFAR) processing. We analyze the relationship between the extracted scatterer distribution and the stage of liver cirrhosis. The ratio of the area in which the amplitude of the processing signal is more than the threshold to the entire processed image area is related quantitatively to the stage of liver cirrhosis. It is found that the proposed technique is valid for the quantitative diagnosis of liver cirrhosis.

在超声成像系统获得的肝脏B超图像中，斑点图案随着肝硬化等疾病的进展而变化。人类肝脏由称为肝小叶的小六边形结构组成。我们提出了一种考虑肝小叶结构的肝组织上散射体分布变化的建模技术，以获得连续阶段的肝硬化肝脏图像。该建模技术可有效分析生物组织特征变化与B型图像变化对肝硬化进展的关系。然后，我们提出了肝脏回波包络的统计特征，以及使用恒定误报率（CFAR）处理从正常和肝硬化肝脏图像中提取散射体分布信息的技术。我们分析了提取的散射体分布与肝硬化阶段之间的关系。处理信号幅度大于阈值的区域占整个处理图像区域的比例与肝硬化的阶段定量相关。研究发现该技术对于肝硬化的定量诊断是有效的。

项目成果

T.Yamaguchi: "Estimation of the Scatterer Distribution of the Cirrhotic Liver using Ultrasonic Image" Jpn.J.Appl.Phys.37. 3093-3096 (1998)

T.Yamaguchi：“使用超声图像估计肝硬化肝脏的散射体分布”Jpn.J.Appl.Phys.37。

Hiroyuki Hachiya: "Two-dimensional measurement of acoustic properties of tissce" Proc.16th International Congress on Acousic. 43-44 (1998)

Hiroyuki Hachiya：“组织声学特性的二维测量”Proc.16th 国际声学大会。

T.Yamaguchi: "The modeling of the Cirrhotic liver for quantitative diagnosis" Japanese Journal of Applied Physics. (1999)

T.Yamaguchi：“用于定量诊断的肝硬化肝脏模型”，日本应用物理学杂志。

T.Yamaguchi: "Estimation of the scatterer distribution of cirrhotic liver" Proc.Ultrasonics World Congress. 392-393 (1997)

T.Yamaguchi：“肝硬化肝脏散射体分布的估计”Proc.Ultrasonics 世界大会。

T.Yamaguchi: "Estimation of the Scatterer Distribution of the Cirrhotic Liver" Japanese Journal of Applied Physics. 37. 3093-3096 (1998)

T.Yamaguchi：“肝硬化肝脏散射体分布的估计”日本应用物理学杂志。