课题基金 / 基金详情

Analysis of a role of Hsp90α in antigen cross presentation

Analysis of a role of Hsp90α in antigen cross presentation
Hsp90α 在抗原交叉呈递中的作用分析
批准号:
22501027
负责人:
UDONO Heiichiro
金额:
$2.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

项目摘要

项目成果

UDONO Heiichiro的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Analysis of a role of Hsp90α in antigen cross presentation In antigen cross-presentation, dendritic cells (DCs) take up extracellular antigens (Ag) and translocate them from the endosome to the cytosol for proteasomal degradation. The molecules responsible for Ag translocation are unknown. By using Hsp90α KO mice, we demonstrated that HSP90 is essential in pulling endosomal Ag out into the cytosol.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Phenotypic analysis of monocyte-derived dendritic cells loaded with tumor antigen with heat-shock cognate protein-70.
对负载有热休克同源蛋白 70 的肿瘤抗原的单核细胞来源的树突状细胞进行表型分析。
DOI: --
发表时间: 2012
期刊: Anticancer Res.
影响因子: --
作者: [Ito S., Nagata Y., Susumu S., Yoneda A, Matsuo M., Yui K., Udono H. Eguchi S and Kanematsu T.]
通讯作者: Udono H. Eguchi S and Kanematsu T.
Newly vaccine strategy with mAbs against heat shock protein 90 (HSP90) on surface of antigen presenting cells.
采用针对抗原呈递细胞表面热休克蛋白 90 (HSP90) 的单克隆抗体的新疫苗策略。
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Shusaku Mizukami, Chihiro Yamazaki, Heiichiro Udono]
通讯作者: Heiichiro Udono
Dendritic cell requires HSP90 as a cytosolic translocator of extracellular antigen for cross-presentation.
树突状细胞需要 HSP90 作为细胞外抗原的胞质转位子以进行交叉呈递。
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [L.Shan, S.Noritake, M.Fujiwara, S.Asano, C.Yoshida-Noro, N.Noro, K.Yamashita, T.Kawakami, Kubo A, 小黒明広, Udono H, Kuroda S, Hayasaka T, 小黒 明広, Heiichiro UDONO]
通讯作者: Heiichiro UDONO
6.RIKEN Research Highlight 2012/02/03 "Holding back Immunity"
6.RIKEN研究亮点2012/02/03“阻碍免疫”
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
32
    Metabolism-based dissection of tumor microenvironment infiltrated by immune cells
    • 批准号:
      18H04033
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $28.04万
    • 财政年份:
      2018
    • 负责人:
      UDONO Heiichiro
    • 依托单位:
    Molecular mechanism of vaccination effect induced by stress protein-Malaria CS antigen
    • 批准号:
      11670245
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.24万
    • 财政年份:
      1999
    • 负责人:
      UDONO Heiichiro
    • 依托单位:
    Investigation of Vaccination Effect by Hsp 70-Malaria Antigen Peptide Complex
    • 批准号:
      06670259
    • 项目类别:
      Grant-in-Aid for General Scientific Research (C)
    • 资助金额:
      $1.28万
    • 财政年份:
      1994
    • 负责人:
      UDONO Heiichiro
    • 依托单位:
    海外基金