Cellular and Immune Responses of Dairy Cows Induced by Intramammary Infusion of Lactic Acid Bacteria and Therapeutic Trials to Quarters of Cows with Mastitis.
Cellular and Immune Responses of Dairy Cows Induced by Intramammary Infusion of Lactic Acid Bacteria and Therapeutic Trials to Quarters of Cows with Mastitis.
批准号:
22580354
负责人:
NAGAHATA Hajime
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
The aim of this study was to characterize the cellular and immune responses of mammary gland by intramammary infusion (IMI) of Lactic acid bacteria (LAB) in cows, and to evaluate the therapeutic effects of IMI of LAB to lactating cows withmastitis. Marked increase of SCC were found in infused quarter at 24-48 hr post infusion. Significantly increased concentrations of immunoglobulins, anti-bacterial proteins and mRNA expression of cytokines on milk leukocytes were found in cows. In therapeutic trials, IMI of LAB to quarters leads to a marked cellular and immune responses in mammary gland. The IMI of LAB may have a possible rolefor control of mastitis.(key words:lactic acid bacteria, mammary gland defense, immune-therapeutic trial, bovine mastitis control)
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Analysis of cellular and immune responses of dairy cows induced by intramammary infusion of lactic acid bacteria and therapeutic trials to quarters of cows with mastitis.
乳房内输注乳酸菌引起的奶牛细胞和免疫反应分析以及对四分之一乳腺炎奶牛的治疗试验。
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Nagahata, H. et al (8)]
通讯作者:
H. et al (8)
DOI:
10.1292/jvms.10-0379
发表时间:
2011-07-01
期刊:
JOURNAL OF VETERINARY MEDICAL SCIENCE
影响因子:
1.2
作者:
[Nagahata, Hajime, Kawai, Hiroatsu, Chang, Chai J.]
通讯作者:
Chang, Chai J.
Analysis of cellular and immune responses of dairy cows induced by intramammary infusion of lactic acid bacteria and therapeutic trials to quarters of cows with mastitis
乳房内输注乳酸菌引起的奶牛细胞和免疫反应分析以及对四分之一乳腺炎奶牛的治疗试验
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Nagahata, H., Moriyama, A., Koshi, A., Mukai, T., Natsume, Y., Higuchi, T., Koike, N. & Ando, T]
通讯作者:
T
Changes in acute-phase proteins and cytokines in serum and milk whey from dairy cows with naturally occurring peracute mastitis caused by Klebsiella pneumonia and the relationship to clinical outcome
肺炎克雷伯菌引起的自然发生的超急性乳腺炎奶牛血清和乳清中急性期蛋白和细胞因子的变化及其与临床结局的关系
DOI:
--
发表时间:
2011
期刊:
J. Vet. Med. Sci
影响因子:
--
作者:
[Hisaeda, K., Arima, H., Sonobe, T., Nasu, M., Hagiwara, K., Kirisawa, R., Takahashi, T., Kikuchi, N. & Nagahata, H]
通讯作者:
H
Characterization of novel Staphylococcus aureus bacteriophages with wide host ranges and their potential as therapeutic agents for bovine mastitis.
具有广泛宿主范围的新型金黄色葡萄球菌噬菌体的特征及其作为牛乳腺炎治疗剂的潜力。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Iwano, H., Higuchi, H., Inoue, H., Kobayashi, H., Nagahata, H., Yokota, H., Tanji, Y., Tamura, Y]
通讯作者:
Y
共 9 条
Intramammary infusion of food-grade lactic acid bacteria (Bifidobacterium breve) on cellular and immuno-modulatory functions in mammary glands and therapeutic trials on bovine mastitis in dairy cows.
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批准号:26450432
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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财政年份:2014
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负责人:NAGAHATA Hajime
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依托单位:
Characterization of host defence capability of dairy cows during peripartum period and modulation of the immunological functions.
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批准号:14360192
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资助金额:$5.89万
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财政年份:2002
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负责人:NAGAHATA Hajime
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依托单位:
Characterization of CD18-Deficient Neutrophil Functions and Some Modulations of Bovine Neutrophils from Cattle with Bovine Leukocyte Adhesion Deficiency
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批准号:11460146
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资助金额:$9.41万
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财政年份:1999
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负责人:NAGAHATA Hajime
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依托单位:
Pathobiology of leukocyte functions from cattle with leukocyte adhesion deficiency(BLAD)and trials of bone marrow transplantation to BLAD-cattle.
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批准号:09660344
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:1997
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负责人:NAGAHATA Hajime
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依托单位:
Characterization of leukocyte functions from cattle with leukocyte adhesion deficiency (BLAD) and prevalence of BLAD-carrier in Holstein cattle in Japan
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批准号:07660426
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.96万
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财政年份:1995
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负责人:NAGAHATA Hajime
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依托单位:
Pathobiology of bovine leukocyte adhesion deficiency in Holstein cattle and its DNA-diagnosis.
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批准号:05660372
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.96万
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财政年份:1993
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负责人:NAGAHATA Hajime
-
依托单位:
海外基金