Antigen specificity and function of lymphocyte in persistent viral infection
Antigen specificity and function of lymphocyte in persistent viral infection
批准号:
22591060
负责人:
NISHIDA Tetsuya
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
PD-1 was associated with exhaustion of CMV-specific CD8+T cells in persistent CMV infection after allogeneic hematopoietic stemcell transplantation. It was suggested that CD33+adherent cells produced IL-6 and regulated PD-1 expression and growth of CMV-specific CD8+T cells through cell-to-cell contact. Serum from patients with persistent CMV infection showed a significantly higher IL-6 level and IL-6 may be useful for a biomarker of persistent CMV infection.
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Correlation of serum IL-6 level with exhaustion of cytomegalovirus-specific T cells after allogeneic hematopoietic stem cell transplantation
异基因造血干细胞移植后血清IL-6水平与巨细胞病毒特异性T细胞耗竭的相关性
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Tanaka J, Kanamori H, Nishiwaki S, Ohashi K, Taniguchi S, Eto T, Nakamae H, Katayama Y, Morishima Y, Suzuki R, Kato K, Sakamaki H, Nishimoto N, Masauzi N, NISHIDA Tetsuya]
通讯作者:
NISHIDA Tetsuya
同種造血幹細胞移植後サイトメガロウイルス感染症の後方視的検討―一元化データを用いた研究―
异基因造血干细胞移植后巨细胞病毒感染的回顾性研究 - 使用集中数据的研究 -
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[西田徹也, 竹中克斗, 森 有紀, 大島久美, 谷口修一, 小川啓恭, 大橋一輝, 岩戸康治, 坂巻 壽, 森島泰雄, 加藤剛二, 鈴木律朗, 福田隆浩]
通讯作者:
福田隆浩
Exhaustion of CMV specific T cells with enhanced PD-1 expression in persistent cytomegalovirus infection after allogeneic stem cell transplantation.
同种异体干细胞移植后持续巨细胞病毒感染中 CMV 特异性 T 细胞耗尽且 PD-1 表达增强。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Kato T, Murase M, Daikoku T, Shiraki K, Murata M, Naoe T]
通讯作者:
Naoe T
Cytotoxic T-lymphocyte antigen 4 haplotype correlates with relapse and survival after allogeneic hematopoietic stem cell transplantation
细胞毒性 T 淋巴细胞抗原 4 单倍型与异基因造血干细胞移植后的复发和生存相关
DOI:
--
发表时间:
2011
期刊:
Bone Marrow Transplant
影响因子:
--
作者:
[Murase M, NishidaT, OnizukaM, InamotoY, SugimotoK, ImahashiN, MurataM, MiyamuraK, KoderaY, InokoH, NaoeT]
通讯作者:
NaoeT
Generation of CMV antigen specific CTL using closed culture system.
使用封闭培养系统生成 CMV 抗原特异性 CTL。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Nishida T, et al.]
通讯作者:
et al.
Development of maximum seismic response estimation method for damage level evaluable next generation seismic evaluation method
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批准号:26420556
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.24万
-
财政年份:2014
-
负责人:NISHIDA Tetsuya
-
依托单位:
Control of inhibitory immunoreceptor in cell therapy after allogeneic hematopoietic stem cell transplantation
-
批准号:25461446
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.24万
-
财政年份:2013
-
负责人:NISHIDA Tetsuya
-
依托单位:
Development of crestal implant for interdental papilla reconstruction
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批准号:24659928
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2012
-
负责人:NISHIDA Tetsuya
-
依托单位:
Immune reaction against tumor-antigen and allo-antigen after cord blood transplantation
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批准号:20890096
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项目类别:Grant-in-Aid for Young Scientists (Start-up)
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资助金额:$2.11万
-
财政年份:2008
-
负责人:NISHIDA Tetsuya
-
依托单位:
海外基金