Development of the diagnostic procedure of the pervasive developmental disorder using the near-infrared spectroscopy

应用ETG4000型52通道近红外光谱仪对42例年龄匹配的健康对照组、精神分裂症组和42例PDD患者进行比较。我们采用词汇流畅性任务进行认知激活，并分析任务期间氧合血红蛋白浓度的平均变化。对于52个通道的每一测量，我们进行了三组之间的单因素方差分析。PDD组和精神分裂症组Ch1和Ch29的激活显著小于健康对照组。在Ch14、Ch25、Ch36和Ch46，健康对照组和PDD组的激活显著大于精神分裂症组。在Ch28中，精神分裂症组的激活显著小于健康对照组。

We compared 42 healthy control group and schizophrenia group which matched age, with 42 patients with PDD using the 52 channels NIRS instrument(ETG4000). We used a word fluency task for a cognitive activation, and analyzed mean change of the oxy-hemoglobin concentration during the task. About each measurement of 52 channels, we conducted the one-way analysis of variance between three groups. Activation was significantly smaller in PDD group and schizophrenia group than the healthy control group in Ch1 and Ch29. Activation was significantly larger than schizophrenia group in the healthy control group and PDD group in Ch14, Ch25, Ch36, and Ch46. Activation was significantly smaller in schizophrenia group than the healthy control group in Ch28.