Validation of the expression and function of Abca5 in osteoclasts and bone tissue.
Validation of the expression and function of Abca5 in osteoclasts and bone tissue.
批准号:
22791786
负责人:
NAKAGAWA Hiroshi
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
The expression of nine and four of 48 ABC transporters were found to be up-and down-regulated during osteoclastgenesis, respectively. Among them, the expression of Abca5 protein was also found to be increased during osteoclastgenesis. Abca5-deficient female mice showed the possibility that Abca5 could activate the bone resorption and/or inhibit bone formation.
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Genetic polymorphism of human ABCC11 as a determinant of earwax type, axillary osmidrosis, and the risk of breast cancer.
人类 ABCC11 的基因多态性是耳垢类型、腋臭和乳腺癌风险的决定因素。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Yu Toyoda, Aki Sakurai, Ikuko Ota, Yasuo Sakai, Tuneaki Gomi, Hiroshi Nakagawa, Alexander Lezhava, Masahiro Nakashima, Koh-ichiro Yoshiura, Yoshihide Hayashizaki, Norio Niikawa, Toshihisa Ishikawa.]
通讯作者:
Toshihisa Ishikawa.
Genetic polymorphisms in human ABC transporter ABCC11 gene.
人类 ABC 转运蛋白 ABCC11 基因的遗传多态性。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Toyoda, Y., Nakagawa, H., Nakashima, M., Yoshiura, K., Niikawa, N., and Ishikawa, T.]
通讯作者:
T.
The low polarity and planar structure of guanidine alkaloids contribute to their interaction with human ABC transporter ABCB1
胍生物碱的低极性和平面结构有助于其与人类 ABC 转运蛋白 ABCB1 的相互作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Nakagawa, H., Tamura, A., Li, S., Aida-Hyugaji, S., Regasini LO, Bolzani Vda S, Hirose, S., Ishikawa, T., Fricker, G., and Efferth, T.]
通讯作者:
T.
Detection of the SNP Q141K in the ABCG2 gene by the SmartAmp method : Molecular biological rationale and clinical applications for gout risk prediction.
通过 SmartAmp 方法检测 ABCG2 基因中的 SNP Q141K:痛风风险预测的分子生物学原理和临床应用。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Wakabayashi-Nakao, K., Aw, W., Nakagawa, H., Furukawa, T., Lezhava, A., Hayashizaki, Y., and Ishikawa, T.]
通讯作者:
T.
アミノレブリン酸を用いたポルフィリン蓄積に関わるトランスポーターの探索
使用氨基乙酰丙酸寻找参与卟啉积累的转运蛋白
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[杉山雄太, 萩谷祐一郎, 林哲也, 土屋京子, 石塚昌宏, 大倉一郎, 小倉俊一郎, ○松本健太郎・萩谷祐一郎・大倉一郎・小倉俊一郎]
通讯作者:
○松本健太郎・萩谷祐一郎・大倉一郎・小倉俊一郎
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