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Development ofa new dental local anesthetic and apply for the needless syringe (SYRIJET)

Development ofa new dental local anesthetic and apply for the needless syringe (SYRIJET)
新型牙科局麻药的开发及应用于无针注射器(SYRIJET)
批准号:
22592289
负责人:
NAKAGAWA Hiroshi
金额:
$3.24万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
The capsaicin/QX-314 group induced longer withdrawal-response latency at 60 to 300 minutes after injection thanthe control. The fluorescence in small- and medium-sized neurons was conspicuous in onlythe dorsal root ganglia injected with capsaicin/QX-314-FAM. These results indicatethat TRPA1 and TRPM8 are ineffective in the transport of QX-314 compared with TRPV1. The capsiate (non-pungent analogue of capsaicin) show the same effects of capsaicin. For this reason, the capsiate may be seen as an alternative to the capsaicin.
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TRPチャネルを用いた新しい局所麻酔薬の開発-TRPV1チャネルとTRPA1チャネルの比較-
利用TRP通道开发新型局部麻醉剂 - TRPV1和TRPA1通道的比较 -
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [中川弘, 山本愛美, 尼寺理恵, 郡由紀子]
通讯作者: 郡由紀子
Roles of Glia, Immune Cells and the Thermo-TRP Channels, TRPV1, TRPA1 and TRPM8, in Pathological Pain
神经胶质细胞、免疫细胞和 Thermo-TRP 通道、TRPV1、TRPA1 和 TRPM8 在病理性疼痛中的作用
DOI: --
发表时间: 2012
期刊: The Open Neuroscience Journal
影响因子: --
作者: [Akio Hiura, Hiroshi Nakagawa]
通讯作者: Hiroshi Nakagawa
Trial to development a new local anaesthetic using TRP channels of TRPV1, TRPA1 and TRPM8
利用 TRPV1、TRPA1 和 TRPM8 的 TRP 通道开发新型局麻药的试验
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Hiroshi Nakagawa, Akio Hiura]
通讯作者: Akio Hiura
An Overview of the Actions of Capsaicin and Its Receptor, TRPV1, and Their Eelations to Small Primary Sensory Neurons
辣椒素及其受体 TRPV1 的作用及其对初级感觉神经元的作用概述
DOI: --
发表时间: 2011
期刊: Anti-Inflammatory & Anti-Allergy Agents
影响因子: --
作者: [樋浦明夫, 中川弘]
通讯作者: 中川弘
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