100% Functional Group Conversion of Polymer Termini via Step Polymerization and the Universality

100%%20Functional%20Group%20Conversion%20of%20Polymer%20Termini%20via%20Step%20Polymerization%20and%20the%20通用性

• 批准号: 22750104
• 负责人: TAKASU Akinori
• 金额: $ 1.75万
• 依托单位: Nagoya Institute of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22750104/
• 关键词: 逐次重合; 官能基変換; 脱水重縮合; ポリエステル; ジオール; 還元; ジチオール; ジハライド; 樹脂硬化剤

We synthesized polyesters via dehydration polycondensation of 3, 3'-dithiodipropioicacid with diols and a, wdihydroxyl polymers including polycaprolactonediol(Mn=1. 6X 103, MW/Mn=1. 8) using scandium catalysts(0. 5 mol%). Subsequently, we performed cleavage of the disulfide linkage to give expected dithiol in good yields. The conversions of the functional group were confirmed by II-1 NMR and MALDI-ToF spectra. We also performed the conversion of 1, 2bis(2azideethoxy) ethane for the corresponding dithiol via "click" polymerization(yield 94%).

以3,3′-二硫代二丙酸为原料，与二醇、聚己内酯二醇（Mn=1）等a， 2羟基聚合物脱水缩聚合成聚酯。6 × 103, MW/Mn=1。8)使用钪催化剂(0。5摩尔%)。随后，我们对二硫键进行了裂解，得到了预期的二硫醇，收率很高。通过II-1 NMR和MALDI-ToF谱证实了官能团的转化。我们还通过“点击”聚合将1,2双（2叠氮乙氧基）乙烷转化为相应的二硫醇（收率94%）。

项目成果

Artificial extracellular matrix proteins containing phenylalanine analogues biosynthesized in bacteria using T7 expression system and the PEGylation.

• DOI: 10.1021/bm200522d
• 发表时间: 2011-09
• 期刊: Biomacromolecules
• 影响因子: 6.2
• 作者: A. Takasu;S. Kondo;Akihiro Ito;Y. Furukawa;M. Higuchi;T. Kinoshita;Inchan Kwon

Functional Group Conversion of Diols via a Dehydration Polycondensation with a Dicarboxylic Acid Containing a Disulide Linkage

通过与含有二硫键的二羧酸脱水缩聚进行二醇的官能团转化

• 发表时间: 2010
• 作者: K.; Ishiguro;F.; Chujo;Y.;高須昭則
• 通讯作者: 高須昭則

Microwave-Assisted Low Temperature Dehydration Polycondensation of Dicarboxylic Acids and Diols Catalyzed by Lewis Acids

路易斯酸催化微波辅助二元酸和二醇低温脱水缩聚

• 发表时间: 2011
• 作者: Naoki Haraguchi;Yu Takemura;Shinichi Itsuno;白川誠司;山田真司・高須昭則
• 通讯作者: 山田真司・高須昭則

Synthesis and Ring-Opening Polymerizations of Novel S-glcooxazolines

新型S-葡萄糖恶唑啉的合成及开环聚合

• 发表时间: 2010
• 期刊: J.Polym.Sci.Part A : Polym.Chem.
• 作者: Kensuke Osada;Theofilus Agrios Tockary;Kazunori Kataoka;高須昭則;高須昭則
• 通讯作者: 高須昭則

Microwave Assisted Low Temperature Dehydration Polycondensation of Dicarboxylic Acids and Diols Catalyzed by Lewis Acids

路易斯酸催化的微波辅助二元酸和二醇的低温脱水缩聚

• 发表时间: 2011
• 作者: 山田真司・高須昭則