The role of cellular prion protein in blood brain barrier
The role of cellular prion protein in blood brain barrier
批准号:
22790178
负责人:
WATANABE Takuya
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
This study aimed to address the role of cellular prion protein(PrPC) in amyloid-beta(Aβ) efflux via blood brain barrier. PrPC knockdown did not affect Aβ transport although other transporters(low density lipoprotein related protein 1 and P-glycoprotein) changed Aβ transport.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
脳血管内皮細胞遊走における正常型プリオン蛋白の役割
正常朊病毒蛋白在脑血管内皮细胞迁移中的作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[日下部紗衣, 渡辺拓也, 安高勇気, 嬉野健一, 西奥剛, 山内淳史, 片岡泰文]
通讯作者:
片岡泰文
脳血管内皮細胞のβ-amyloid排泄機構における炎症性サイトカインの役割
炎症细胞因子在脑血管内皮细胞β-淀粉样蛋白排泄机制中的作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[大平信太郎, 渡辺拓也, 平賀千絵, 道具伸也, 山内淳史, 片岡泰文]
通讯作者:
片岡泰文
Involvement of the cellular prion protein in the migration of brain microvascular e ndothelial cells
细胞朊病毒蛋白参与脑微血管内皮细胞的迁移
DOI:
10.1016/j.neulet.2011.03.096
发表时间:
2011
期刊:
Neurosci Lett.
影响因子:
--
作者:
[Watanabe T, Yasutaka Y, Nishioku T, Ku sakabe S, Futagami K, Yamauchi A, Kata oka Y]
通讯作者:
Kata oka Y
Semiclassical analysis of spectral and scattering problems associated with energy crossings
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批准号:15K17563
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
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财政年份:2015
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负责人:WATANABE Takuya
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资助金额:$2.75万
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财政年份:2012
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Research on the problems of merging turning points via the semi-classical and microlocal analysis
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Therapeutic Strategy of Diabetic Macroangiopathy using the Gut Hormone Incretin
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2010
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负责人:WATANABE Takuya
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Elucidation of the mechanisms regulating bone metastasis and invasion via the interaction between tumor and bone microenvironment.
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批准号:21791381
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
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财政年份:2009
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负责人:WATANABE Takuya
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依托单位:
Delivery of siRNA to central nervous system viablood-brain barrirer transport : Therapy for prion disease
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批准号:20800066
-
项目类别:Grant-in-Aid for Young Scientists (Start-up)
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资助金额:$2.11万
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财政年份:2008
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负责人:WATANABE Takuya
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依托单位:
Mechanisms of Macrophage Foam Cell Formation and Hypertensive Complications Caused by Vasoactive Agents
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批准号:18590824
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.46万
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财政年份:2006
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负责人:WATANABE Takuya
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依托单位:
Analysis of transcription factors and of crosstalk between proteinase and extracellular matrix that are related to invasive process of glioblastoma
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批准号:15390431
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.09万
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财政年份:2003
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负责人:WATANABE Takuya
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依托单位:
海外基金