Cell stimulation using direct vibration with magnetic beads and development of a measurement system

使用磁珠直接振动刺激细胞并开发测量系统

• 批准号: 22650100
• 负责人: MASUZAWA Toru
• 金额: $ 2.07万
• 依托单位: Ibaraki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22650100/
• 关键词: 再生医用工学; 細胞刺激; 磁性微粒子; 振動検出; 交番磁界; レーザトラップ

Cell stimulation system using direct viblation with magnetic beads, which has a diameter of several micro meters, attached on the cell wall has been developed to investigate the expression of cell function with the vibration stimuli. The attaced magnetic beads are vibrated with an alternating magnetic field and the vibration amplitude is measured by newly developed optical system. The magnetic beads were vibrated with maximum oscilation amplitude of 451 nm with a excitation frequency of 80 Hz.

为了研究振动刺激对细胞功能表达的影响，研制了一种利用磁珠直接振动的细胞刺激系统。磁珠直径为几微米，附着在细胞壁上。在交变磁场作用下，吸附的磁珠发生振动，并利用新开发的光学系统测量振动幅度。磁珠以451 nm的最大振荡振幅和80 Hz的激发频率振动。