Establishment of research basis for nutrigenomics-based nutritional education

在这项研究中，我们试图建立一个战略，开发一个新的程序，营养教育的基础上，分子营养与遗传因素影响饮食习惯，行为和生活方式相关疾病的发病机制。作为一个有代表性的研究模型，我们调查了遗传因素与膳食磷酸盐摄入量、餐后血清P水平、内皮功能和食欲之间的关系。我们的研究结果表明，我们的策略是有效的，以分析膳食摄入量和营养代谢，饮食行为，血清标志物，或病理生理功能与遗传因素之间的关系的个体差异。该战略可使我们制定一项量身定制的营养教育战略，以预防各种与生活方式有关的疾病。

In this study, we attempted to establish a strategy to development a new procedure for nutritional education based on molecular nutrition with genetic factors affecting eating habits, behaviors, and pathogenesis of life-style related diseases. As a representative research model, we investigated the relationships between genetic factors and dietary phosphate intake, post-prandial serum P levels, endothelial function, and appetite. Our results suggest that our strategy was effective to analyze the individual differences in the relationships between dietary intake and nutrient metabolism, eating behavior, serum markers, or patho-physiological function with genetic factors. The strategy may enable us to develop a tailor-made strategy of nutritional education to prevent various life-style related diseases.