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Search for anti-malaria agents from marine organisms

Search for anti-malaria agents from marine organisms
从海洋生物中寻找抗疟疾药物
批准号:
22658065
负责人:
MATSUNAGA Shigeki
金额:
$2.25万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

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英文摘要
We searched for compounds selectively toxic against malaria parasites from marine organisms. The bioassay was examined to see differential antimicrobial activity against bacteria dependent on mavalonate pathway and non-mevalonate pathway. We screened the 736 extracts of marine invertebrates collected along the coast of Japan. Active compounds from hit organisms were isolated and their structures were elucidated. We characterized several compounds from an unidentified marine sponge from Kagoshima and a soft coral from Tanegashima. The selectivities of the isolated compounds were not noteworthy.
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Generation of metal-carbene species without using diazo-comoounds and its synthetic application
  • 批准号:
    15K13686
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.58万
  • 财政年份:
    2015
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    MATSUNAGA Shigeki
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Asymmetric C-H Bond Functionalization with Heterodinuclear Asymmetric Catalysts
Innovative Molecular Transformation and Drug Lead Development Based on Fine Design of Multinuclear Catalysis
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  • 财政年份:
    2011
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    MATSUNAGA Shigeki
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Inter ionic interaction and dynamics in liquid and solid electrolyte by molecular dynamics simulation
  • 批准号:
    22540337
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
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    $2.75万
  • 财政年份:
    2010
  • 负责人:
    MATSUNAGA Shigeki
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国内基金
海外基金
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  • 批准号:
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    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2026
  • 负责人:
    周永生
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珠江口近岸海域初级生产力结构特征及其形成机制
海洋生物资源创新利用与可持续发展-海藻寡糖生物资源创新利用与可持续发展
  • 批准号:
    2025C02088
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    蒋剑平
  • 依托单位:
海洋生物资源创新利用与可持续发展-大黄鱼大规格苗种高效绿色牧场化培育模式集成与创新