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Mouse models of Autoimmune hearing loss generated by a transgenic approach and its implication

Mouse models of Autoimmune hearing loss generated by a transgenic approach and its implication
转基因方法产生的自身免疫性听力损失小鼠模型及其意义
批准号:
22659309
负责人:
OGAWA Kaoru
金额:
$2.18万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

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中文摘要
翻译
通过产生在内耳毛细胞中特异性表达HA抗原的转基因小鼠(Math-HA)来建立自身免疫性听力损失模型。通过过继性转移来自CL 4小鼠的淋巴细胞,小鼠在h
英文摘要
Autoimmune hearing loss models were established by generating a transgenic mouse (Math-HA) that specifically expresses HA antigen in the inner ear hair cells. By an adoptive transfer of lymphocytes derived from CL4mice, the mice suffered hearing loss at h
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DOI: 10.1159/000310352
发表时间: 2010-01-01
期刊: ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES
影响因子: --
作者: [Ide, Rika, Harada, Tatsuhiko, Ogawa, Kaoru]
通讯作者: Ogawa, Kaoru
Notch Signaling Alters Sensory of Neuronal Cell Fate Specification of Inner Ear Stem Cells
Notch信号改变神经元细胞的感觉 内耳干细胞的命运规范
DOI: --
发表时间: 2011
期刊: J.Neurosci.
影响因子: --
作者: [Fujioka M, Jeon SJ, Kim SC, Edge AS]
通讯作者: Edge AS
Pure tone auditory thresholds can change according to duration of interrupted tones in patients with psychogenic hearing loss
心因性听力损失患者的纯音听阈可能会根据中断音的持续时间而变化
DOI: --
发表时间: 2011
期刊: Acta Otolaryngol.
影响因子: --
作者: [Oishi N, Inoue Y, Ogawa K他3名]
通讯作者: Ogawa K他3名
DOI: 10.1016/j.anl.2010.09.007
发表时间: 2011-06-01
期刊: AURIS NASUS LARYNX
影响因子: 1.7
作者: [Minami, Shujiro B., Shinden, Seiichi, Ogawa, Kaoru]
通讯作者: Ogawa, Kaoru
共 16 条
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