Does cytokine directly reacted with bacteria?

本研究的目的是为了证明细胞因子的新功能。我们研究了细胞因子的抑菌活性、细胞因子对细菌细胞的亲和力以及细胞因子处理对细菌附着于哺乳动物细胞的影响。我们发现，带正电荷的多肽MIP3alpha和IL8能够结合细菌细胞，抗菌作用较弱，而细胞因子对细菌细胞的粘附作用对细菌对哺乳动物细胞的附着没有影响。综上所述，一些细胞因子与细菌结合，调节免疫反应

The purpose of this research is to demonstrate the new function of cytokines. We investigated the antibacterial activity of cytokines, the cytokine affinity to bacterial cells and the effect of cytokine treatment on bacterial attachment to mammal cells. We found that MIP3alpha and IL8, positive charged peptides, were able to bind bacterial cells, and had weak antibacterial effect, while biding of cytokines to bacterial cells had no effect on the bacterial attachment to mammal cells. In conclusion, it is suggested that some cytokines binds to bacteria causing to modulate the immune responses