A Study on Ultrasonic Measurement and Visualization of Propagation of Myocardial Contraction Response

心肌收缩反应传播的超声测量和可视化研究

• 批准号: 23360177
• 负责人: KANAI Hiroshi
• 金额: $ 12.65万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23360177/
• 关键词: 心臓疾患; 医用超音波工学; 心臓壁弾性特性; 位相差トラッキング法; 電気的興奮伝導; 心筋収縮特性; 収縮応答伝播速度; 超音波診断; 位相差トラキング法; 超音波診断装置; 位相差ﾄﾗｯｷﾝｸﾞ法; 収縮波面

For realization of non-invasive regional myocardial tissue characterization, in the present study, we tried to elucidate the characteristic of the myocardial response to the electrical excitation by an in vitro experiment using an excised rat left-ventricular wall. To visualize such propagation phenomenon, whose propagation speed is up to several m/s, high frame rate ultrasound was used. Propagation of the myocardial vibration was visualized by estimating the delay time between vibration waveforms measured in the reference ultrasonic beam and each ultrasonic beam using the cross-correlation function between the vibration waveforms. From the estimated delay time, we visualized the propagation of myocardial vibration caused by the electrical excitation. Propagation velocities were estimated to be 2.5 m/s at the internal and external surfaces of the left-ventricular wall. These results correspond to the results obtained in in vivo experiments measured with high frame rate ultrasound.

为了实现无创性局部心肌组织定征，本研究采用离体大鼠左心室壁，探讨心肌对电刺激的反应特点。为了可视化传播速度高达几m/s的这种传播现象，使用了高帧率超声。通过使用振动波形之间的互相关函数估计在参考超声波束和每个超声波束中测量的振动波形之间的延迟时间，来可视化心肌振动的传播。从估计的延迟时间，我们可视化的电激励引起的心肌振动的传播。左心室壁内外表面的传播速度估计为2.5 m/s。这些结果对应于用高帧率超声测量的体内实验中获得的结果。

项目成果

Nano-Biomedical Engineering 2012

纳米生物医学工程2012

• 发表时间: 2011
• 作者: Hideyuki Hasegawa;Hiroshi Kanai
• 通讯作者: Hiroshi Kanai

Automated Identification of the Heart Wall Throughout the Entire Cardiac Cycle Using Optimal Cardiac Phase for Extracted Features

使用最佳心脏相位提取特征，自动识别整个心脏周期的心壁

• DOI: 10.1143/jjap.50.07hf16
• 发表时间: 2011
• 期刊: Japanese Journal of Applied Physics
• 影响因子: 1.5
• 作者: Hiroki Takahashi;Hideyuki Hasegawa;and Hiroshi kanai
• 通讯作者: and Hiroshi kanai

Detection of Arterial Wall Boundaries Using an Echo Model Composed of Multiple Ultrasonic Pulses

使用由多个超声波脉冲组成的回波模型检测动脉壁边界

• 发表时间: 2012
• 作者: Nabilah Ibrahim;Hideyuki Hasegawa;and Hiroshi Kanai;高橋広樹，長谷川英之，金井 浩;小松洋介,長岡亮,太田信,船本健一,早瀬敏幸,金井浩,西條芳文;Nabilah Ibrahim，長谷川英之，金井 浩
• 通讯作者: Nabilah Ibrahim，長谷川英之，金井 浩

Suppression of Point Spread Function from Ultrasonic Echoes for Speckle Reduction in the Ultrasonography

超声回波点扩散函数的抑制以减少超声检查中的散斑

• 发表时间: 2012
• 作者: Sho Kageyama;Hideyuki Hasegawa;Hiroshi Kanai
• 通讯作者: Hiroshi Kanai

頸動脈壁内膜面への適用を目指した表面粗さ高精度推定における計測範囲の拡張Expansion of Region of Accurate Estimation of Surface Roughness for Application to Carotid Luminal Surface

颈动脉管腔表面表面粗糙度精确估计区域的扩展

• 发表时间: 2011
• 作者: 北村浩典;長谷川英之;金井浩
• 通讯作者: 金井浩