Research on the mechanism of visceral fat accumulation in postmenopausal women.
Research on the mechanism of visceral fat accumulation in postmenopausal women.
批准号:
23592433
负责人:
TAKAHASHI Kazuhiro
金额:
$3.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013
中文摘要
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英文摘要
The cortisol/cortisone ratio and the expression of 11beta-HSD1 mRNA in visceral fatin postmenopausal women were significantly higher than those in premenopausal women. There was a significant correlation between the E1/E2 ratio of visceral fat and body mass index in postmenopausal women. A significant correlation between the cortisol/cortisone ratio and the E1/E2 ratio of visceral fat was observed in postmenopausal women.The expression of 11beta-HSD1 mRNA in visceral fat increases in postmenopausal women, and the E1/E2 ratio in visceral fat may be associated with local glucocorticoid levels after menopause. The concentrations of fatty acid metabolites in the visceral fat of postmenopausal women were significantly higher than those in the visceral fat of premenopausal women. The change in fatty acid metabolism in visceral adipose tissues might be related to metabolic syndrome in postmenopausal women.
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Differences in fatty acid metabolism in visceral and subcutaneous adipose tissues in postmenopausal women: an analysis using metabolomics.
绝经后妇女内脏和皮下脂肪组织脂肪酸代谢的差异:利用代谢组学进行分析。
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Yokoyama Y, Kurachi H, Yamatani H]
通讯作者:
Yamatani H
Differences in fatty acid metabolism of visceral adipose tissue in postmenopausal women
绝经后妇女内脏脂肪组织脂肪酸代谢的差异
DOI:
--
发表时间:
2014
期刊:
Menopause
影响因子:
2.7
作者:
[Yamatani H, Takahashi K, Yoshida T, Soga T, Kurachi H]
通讯作者:
Kurachi H
Deterioration in fatty acid metabolism of visceral adipose tissue in postmenopausal women
绝经后妇女内脏脂肪组织脂肪酸代谢恶化
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Yamatani H, Takahashi K, Urushiyama K, Sudo T, Ohta T, Soga T, Kurachi H.]
通讯作者:
Kurachi H.
Association of estrogen with glucocorticoid levels in visceral fat in postmenopausal women
绝经后妇女雌激素与内脏脂肪糖皮质激素水平的关系
DOI:
--
发表时间:
2013
期刊:
Menopause
影响因子:
2.7
作者:
[Yamatani H, Takahashi K, Yoshida T, Takata K, Kurachi H]
通讯作者:
Kurachi H
閉経後の内臓脂肪におけるグルココルチコイド活性化制御機構の解析
绝经后内脏脂肪糖皮质激素激活控制机制分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Tadakawa M, Takeda T, Li B, Tsuiji K, Yaegashi N, 武田卓, 山谷日鶴,高橋一広,竹原功,松村創平,須藤毅,吉田隆之,倉智博久]
通讯作者:
山谷日鶴,高橋一広,竹原功,松村創平,須藤毅,吉田隆之,倉智博久
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