Early diagnosis of the possibility of severe sepsis using NMR

在提取去除的脑并对提取物进行NMR测量后，分析NMR数据。结果发现，L P S（10 mg / kg/d和2 mg / kg）和生理盐水处理组在给药后6小时内均出现分离。6小时内无大鼠死亡。这一发现表明，通过这种方法可以识别脓毒症及其在早期脓毒症脑中的严重程度。虽然这一发现是从离体实验，我们认为这是重要的知识，导致早期诊断的可能性严重脓毒症与体内MRS，因为大脑有较少的运动，它是非常适合在体内MRS测量。

After extracting the removed brains and performing NMR measurement of the extracts, NMR data were analized. We found that 3 groups of L P S (10 mg / kg/day and 2 mg / kg) and saline treated were isolated in 6 hours after administration. No rats died within 6 hours. This finding suggests the possibility of identification of sepsis and its severity in the brain of early sepsis by this method. Although this finding is from ex vivo experiment, we consider it is important knowledge leading to early diagnosis of the possibility of severe sepsis with in vivo MRS sinse brain has less movement and it is very suitable for in vivo MRS measurement.