Basic research about bone regeneration and oral implant for craniofacial defect patients
Basic research about bone regeneration and oral implant for craniofacial defect patients
批准号:
23593054
负责人:
NAKAMURA Hiroshi
金额:
$3.24万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013
中文摘要
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英文摘要
We generated systemic Ryk signal deficient mice. Ryk deficient mice exhibited a cleft palate and totally decrease of osteoclast number and osteoblast number in bone. Furthermore, we generated osteoclast-specific Ryk-deficient mice and osteoblast-specific Ryk-deficient mice. Interestingly, there are no cleft palate in both osteoclast-specific Ryk-deficient mice and osteoblast-specific Ryk-deficient mice. Osteoclast-specific Ryk-deficient mice have normal bone phenotype. These results suggest that Ryk expression in osteoclasts and osteoblasts is not essential for craniofacial defect.
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BMP誘導性異所性骨形成における破骨細胞の役割
破骨细胞在 BMP 诱导异位骨形成中的作用
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[中村美どり]
通讯作者:
中村美どり
Stimulation of bone formation in cortical bone of mice treated with a receptor activator of nuclear factor-κB ligand (RANKL)-binding peptide that possesses osteoclastogenesis inhibitory activity.
用核因子 - κB配体(RANKL)结合肽的受体激活剂治疗的小鼠的皮质骨刺激骨形成,该肽具有破骨构成抑制活性。
DOI:
10.1074/jbc.m112.426080
发表时间:
2013-02-22
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
[Furuya Y, Inagaki A, Khan M, Mori K, Penninger JM, Nakamura M, Udagawa N, Aoki K, Ohya K, Uchida K, Yasuda H]
通讯作者:
Yasuda H
BMP誘導性異所性骨における破骨細胞の役割
破骨细胞在 BMP 诱导异位骨中的作用
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Yanagita M, Kojima Y, Mori K, Yamada S and Murakami S, 中村美どり]
通讯作者:
中村美どり
DOI:
10.5312/wjo.v3.i11.175
发表时间:
2012-11
期刊:
World journal of orthopedics
影响因子:
1.9
作者:
[T. Yamashita;N. Takahashi;N. Udagawa]
通讯作者:
T. Yamashita;N. Takahashi;N. Udagawa
Osteoclast Cell Lineage : Characteristics and behavior of osteoclast precursors in vivo
破骨细胞谱系:体内破骨细胞前体的特征和行为
DOI:
--
发表时间:
2014
期刊:
Encyclopedia of Human Body 3rd Edition
影响因子:
--
作者:
[Takahashi N, Kobayashi Y, Nakamura M, Udagawa N (他3名)]
通讯作者:
Udagawa N (他3名)
共 16 条
Research on Data Resident Computing
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批准号:22650008
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.2万
-
财政年份:2010
-
负责人:NAKAMURA Hiroshi
-
依托单位:
Matrix metalloproteinase-3 in a stable form, a novel medicament for pulpitis
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批准号:21390512
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.56万
-
财政年份:2009
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负责人:NAKAMURA Hiroshi
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依托单位:
Study of Crude Bone Morphogenetic Protein(BMP)for use as Pulp-Capping Material
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批准号:18592103
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.07万
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财政年份:2006
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负责人:NAKAMURA Hiroshi
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依托单位:
Architecture and Circuit-Level Co-Design for Low-Power High-Performance Microprocessor
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批准号:18200002
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$31.28万
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财政年份:2006
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负责人:NAKAMURA Hiroshi
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依托单位:
Analytical Application of Molecular Recognition by Photochemistry of Excited States
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批准号:16550064
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2004
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负责人:NAKAMURA Hiroshi
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依托单位:
Analysis of tooth development of osteoprotegerin- deficient mice
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批准号:15592180
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2003
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负责人:NAKAMURA Hiroshi
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依托单位:
Development of the quantitative method to monitor rare insects on mountainous areas of central Japan
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批准号:15510191
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2003
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负责人:NAKAMURA Hiroshi
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依托单位:
Does the host specific races of the common cuckoo evolve with the gene by the side of female lineages?
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批准号:14340243
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.51万
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财政年份:2002
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负责人:NAKAMURA Hiroshi
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依托单位:
Low-Power and High-Performance Processor based on Co-optimization of Architecture and Compiler
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批准号:14380136
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.56万
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财政年份:2002
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负责人:NAKAMURA Hiroshi
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依托单位:
Influence of immune mechanism on aging in articular cartilage, -Immune response and responsible proteins in osteoarthritis-
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批准号:13671547
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:2001
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负责人:NAKAMURA Hiroshi
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依托单位:
Research of bacteria related to periapical diseases activate MMP and inactivate TIMP
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批准号:13672015
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2001
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负责人:NAKAMURA Hiroshi
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依托单位:
Experimental Periapical Lesion in Non-insulin Dependent Diabetic Rat (GK Rat).
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批准号:09671973
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
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财政年份:2000
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负责人:NAKAMURA Hiroshi
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依托单位:
The analysis of Industrial Location, Employment and Productivity of Manufacturing using Geographical Information System tools
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批准号:12630065
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2000
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负责人:NAKAMURA Hiroshi
-
依托单位:
Immunological study for osteoarthritis focusing on T cells.
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批准号:11671461
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.73万
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财政年份:1999
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负责人:NAKAMURA Hiroshi
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依托单位:
Development of Fluorescent Reagents for Chirality Recognition Based on π-Electron Interaction
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批准号:11440214
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.23万
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财政年份:1999
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负责人:NAKAMURA Hiroshi
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依托单位:
Research on Software Controlled Integrated Memory Architecture for Large Scientific Computing
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批准号:10680335
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:1998
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负责人:NAKAMURA Hiroshi
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依托单位:
Development of Polyether Type Chromogenic Reagents Based on Interaction between Aromatic π-Electrons
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批准号:09555260
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.62万
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财政年份:1997
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负责人:NAKAMURA Hiroshi
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依托单位:
ESTABLISHMENT OF BASIC MATERIAL FOR BUILDINGS IN PACIFIC AREA
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批准号:08044157
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$3.52万
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财政年份:1996
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负责人:NAKAMURA Hiroshi
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依托单位:
CONSTRUCTION OF BIOLOGICAL PHOSPHORYLATION ANALYZING SYSTEM BASED ON THE CHEMOAFFINITY OF TITANIA
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批准号:07557298
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$3.26万
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财政年份:1995
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负责人:NAKAMURA Hiroshi
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依托单位:
Effect of humic substance on diffusion and toxicity of environmental polutants and application of it as clean up reagent
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批准号:07558205
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$1.54万
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财政年份:1995
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负责人:NAKAMURA Hiroshi
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依托单位:
海外基金