Development of the microcirculation functional measuring method by pressurization optical sensing

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In order to measure the amount of blood of microcirculation in papillary layer of skin, a optical sensing with pressurization mechanism was proposed. As an application of the proposed method, the change of blood amount by flow mediated dilatation was measured. A parameter of pulsation origin of the arteriole obtained by this technique showed goodcorrelation with the conventional method. However, parameters about microcirculation indicated inherent responses which are different from the conventional method. This result shows a possibility that novel information about microcirculation will be acquired by the proposing method.