A study evaluating the effects of physical therapy on rat models of neuropathic pain based on electrophysiological parameters

采用运动训练（游泳）、经皮电逆神经刺激（TENS）和全身振动等方法，观察物理疗法对神经元损伤所致大鼠慢性疼痛模型的影响。TENS可逆转神经缩窄引起的大鼠热痛阈降低。除坐骨神经损伤外，踝关节制动成功地建立了慢性疼痛模型。怀疑支配损伤肢体的感觉神经（背根神经节神经元）的电生理特性改变，如TTX敏感性钠通道表达增加。

Effects of physical therapy on the chronic pain model of rat induced by neuronal damage was tested by using exercise training (swimming), transcutaneous electrical reversed nerve stimulation (TENS) and whole-body vibration. TENS reversed lowered thermal pain threshold of rats induced by nerve constriction. In addition to neuronal damage of sciatic nerve, immobilization of ankle joint successfully established a chronic pain model. Alteration of electrophysiological property, such as increased expression of TTX-sensitive sodium channels, of sensory nerve (dorsal root ganglion neuron) innervating the injured limb was suspected.