Development of novel drug delivery system for micro RNA nucleic biomedicine using exosome from human cultured cells
Development of novel drug delivery system for micro RNA nucleic biomedicine using exosome from human cultured cells
批准号:
23650626
负责人:
TAHARA Hidetoshi
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 --
中文摘要
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英文摘要
We have developed Cd44-GFP expressing cells including normal and cancer cell lines to visualized exosomes. We also purified CD44-GFP labeled exosomes form those cells. We confirmed that CD44-GFP labeled exosomes cargo microRNA by adding these exosomes to the other cells. These tools should be useful for exosome derived DDS technology.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Visualization of senescence secreted exosome.
衰老分泌的外泌体的可视化。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[岡田恵, 中村亜由美, 小坂展慶, 落谷孝広, 田原栄俊]
通讯作者:
田原栄俊
DOI:
10.1083/jcb.201010100
发表时间:
2011-04-18
期刊:
The Journal of cell biology
影响因子:
--
作者:
[Xu D, Takeshita F, Hino Y, Fukunaga S, Kudo Y, Tamaki A, Matsunaga J, Takahashi RU, Takata T, Shimamoto A, Ochiya T, Tahara H]
通讯作者:
Tahara H
Study of solutions and their singularities of nonlinear partial differential equations in the complex domain
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批准号:15K04966
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2015
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负责人:TAHARA Hidetoshi
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依托单位:
Development of novel cancer specific DDS utilizing circulating microRNA-derived mechanism
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批准号:24650645
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2012
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负责人:TAHARA Hidetoshi
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依托单位:
Mechanism of senescence-associated microRNA inhibiting cell growth and metastasis
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批准号:23300363
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$14.06万
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财政年份:2011
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负责人:TAHARA Hidetoshi
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依托单位:
A STUDY OF SINGULARITIES OF SOLUTIONS OF NONLINEAR PARTIAL DIFFERENTIAL EQUATIONS IN THE COMPLEX DOMAIN
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批准号:22540206
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.58万
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财政年份:2010
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负责人:TAHARA Hidetoshi
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依托单位:
Risk assessment of cancer using telomere G-tail length measurement
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批准号:20014015
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$10.24万
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财政年份:2008
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负责人:TAHARA Hidetoshi
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依托单位:
A STUDY OF SINGULARITIES IN NONLINEAR PARTIAL DIFFERENTIAL EQUATIONS IN THE COMPLEX DOMAIN
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批准号:19540197
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.66万
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财政年份:2007
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负责人:TAHARA Hidetoshi
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依托单位:
Elucidation of the consequence of telomere single-stand overhang, G-tail, in biology, and application to age-related disease
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批准号:18390027
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.66万
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财政年份:2006
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负责人:TAHARA Hidetoshi
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依托单位:
Study of singularities of partial differential equations in the complex domain
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批准号:16540169
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2004
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负责人:TAHARA Hidetoshi
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依托单位:
Identification of compounds that induce or repress telomerase activity
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批准号:15590061
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2003
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负责人:TAHARA Hidetoshi
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依托单位:
Study of singularities of solutions of partial differential equations in the complex domain
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批准号:14540185
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.92万
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财政年份:2002
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负责人:TAHARA Hidetoshi
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依托单位:
Study of singularities in partial differential equations
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批准号:12640189
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.79万
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财政年份:2000
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负责人:TAHARA Hidetoshi
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依托单位:
Do telomere regulate in vivo aging?
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批准号:12672111
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:2000
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负责人:TAHARA Hidetoshi
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依托单位:
海外基金