Development and application of novel calcium-sensitive protein splicing systems
Development and application of novel calcium-sensitive protein splicing systems
批准号:
23651216
负责人:
FUTAKI Shiroh
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
Calmodulin C-terminal domain peptides formed a heterodimer in the presence of calcium. Aiming at its application to protein splicing, detailed modes of heterodimer formation of these peptides are under study. On the other hand, an ion-channelprotein was constructed using the calmodulin C-terminal segment. The channel opened in the presence of calcium, and thus artificial calcium-sensitive ion channel was successfully established.
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細胞内安定型ユビキチン多量体の構築のための新しいアプローチ
构建细胞内稳定泛素多聚体的新方法
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[奥彰彦, 游 晧欣, 中瀬生彦, 二木史朗]
通讯作者:
二木史朗
Peptide tools for controlling and analyzing cell functions
用于控制和分析细胞功能的肽工具
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[TU Kai-Min, 狩野 康人, 櫻庭 俊, 松林 伸幸, Shiroh Futaki]
通讯作者:
Shiroh Futaki
Construction of a calcium-gated artificial channel by fusing alamethicin with a calmodulin sensor proteinPeptide Science 2012
通过融合阿拉甲辛与钙调蛋白传感器蛋白构建钙门控人工通道Peptide Science 2012
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Daisuke Noshiro, Kazuhiro Sonomura, Hao-Hsin Yu, Miki Imanishi, Koji Asami, Shiroh Futaki]
通讯作者:
Shiroh Futaki
カルモジュリンCドメインを用いたカルシウム感受性人工イオンチャネルの創製
使用钙调蛋白 C 结构域创建钙敏感人工离子通道
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[能代大輔, 園村和弘, 浅見耕司, 二木史朗]
通讯作者:
二木史朗
Construction of a Ca2+-gated Artificial Channel by Fusing Alamethicin with a Calmodulin-derived Extramembrane Segment
通过将阿拉美辛与钙调蛋白衍生的膜外片段融合构建 Ca2 门控人工通道
DOI:
10.1021/bc300468x
发表时间:
2013
期刊:
Bioconjug. Chem
影响因子:
--
作者:
[Daisuke Noshiro, Kazuhiro Sonomura, Hao-Hsin Yu, Miki Imanishi, Koji Asami, Shiroh Futaki]
通讯作者:
Shiroh Futaki
共 7 条
Library design and selection for obtaining peptides that target HTLV-1 protein
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批准号:25560401
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
-
财政年份:2013
-
负责人:FUTAKI Shiroh
-
依托单位:
Chemical Biology in internalization of membrane-permeable peptides
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批准号:19209004
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$32.86万
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财政年份:2007
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负责人:FUTAKI Shiroh
-
依托单位:
Development of intracellular targeting peptide vectors and the real-time observation in cells.
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批准号:17390029
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.73万
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财政年份:2005
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负责人:FUTAKI Shiroh
-
依托单位:
Design and intracellular delivery of peptides for transcription regulation
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批准号:14370720
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.15万
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财政年份:2002
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负责人:FUTAKI Shiroh
-
依托单位:
Design and intracellular delivery of peptides for transcription regulation
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批准号:12557200
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.58万
-
财政年份:2000
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负责人:FUTAKI Shiroh
-
依托单位:
Efficient translocation of hybrid peptides through cell membrane for the control of transcription
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批准号:10671987
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.73万
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财政年份:1998
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负责人:FUTAKI Shiroh
-
依托单位:
海外基金