Mother infant interaction in depressive mothers using Near-infrared spectroscopy(NIRS)

使用近红外光谱（NIRS）研究抑郁母亲的母婴互动

• 批准号: 23653199
• 负责人: HONJO Shuji
• 金额: $ 1.75万
• 依托单位: Nagoya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23653199/
• 关键词: 母子相互作用; NIRS; 産後うつ病; 近赤外線分光法

The objective of this study was to examine differences in the prefrontal cortex blood flow in babies when cuddled by their depressed mothers and their normal mothers. The depressive emotions of the mothers were measured using the Edinburgh PostnatalDepression Scale (EPDS). Then, by using near infrared spectroscopy (NIRS), the changes in the cerebral blood flow were measured while mothers with high EPDS scores and those with low scores interacted with their babies. The results showed that when mothers with high depression scores interacted with their babies, no major changes in hemoglobin concentrations occurred before and after the interaction; however, the oxyhemoglobin concentrations increased immediately after the interaction began. This suggests that changes in the cerebral blood flow duringmother-child interactions vary depending on the level of depression that the mother is experiencing. However, further data are required to carefully verify the reproducibility of these results.

这项研究的目的是检测婴儿在被抑郁的母亲和正常的母亲拥抱时前额叶皮层血流的差异。采用爱丁堡产后抑郁量表（EPDS）测量母亲的抑郁情绪。然后，通过近红外光谱（NIRS），测量大脑血流的变化，而与EPDS得分高的母亲和那些得分低的母亲与他们的婴儿互动。结果表明，当抑郁得分高的母亲与婴儿互动时，在互动前后血红蛋白浓度没有发生重大变化;然而，在互动开始后，氧合血红蛋白浓度立即增加。这表明，在母子互动过程中，脑血流的变化取决于母亲所经历的抑郁程度。然而，需要进一步的数据来仔细验证这些结果的重现性。

项目成果

Hemodynamic changes in infants' prefrontal cortex when viewing maternal facial expressions: A near-infrared spectroscopic study

观察母亲面部表情时婴儿前额皮质的血流动力学变化：一项近红外光谱研究

• 发表时间: 2011
• 作者: Yamamoto H;Yoshikawa T;Ito H;Nomura K;Yasunaga K;& Kaneko H
• 通讯作者: & Kaneko H

Near-Infrared Spectroscopic Assessment of Haemodynamic Activation in the Cerebral Cortex - A Review in Developmental Psychology and Child Psychiatry (In) Infrared Spectroscopy - Life and Biomedical Sciences

大脑皮层血流动力学激活的近红外光谱评估 - 发展心理学和儿童精神病学综述 (In) 红外光谱 - 生命与生物医学科学

• 发表时间: 2012
• 作者: Kaneko H;Yoshikawa T;Ito H;Nomura K;Okada T & Honjo S;Kaneko Hitoshi
• 通讯作者: Kaneko Hitoshi

HEMODYNAMIC ACTIVATION IN INFANTS' PREFRONTAL AND OCCIPITAL CORTICES WHEN VIEWING MATERNAL FACIAL EXPRESSIONS : A NEAR-INFRARED SPECTROSCOPIC STUDY

观察母亲面部表情时婴儿前额叶和枕叶皮质的血流动力学激活：一项近红外光谱研究

• 发表时间: 2011
• 作者: Hiroko Yamamoto;Toru Yoshikawa;Hiroyuki Ito;Kenji Nomura;Kazuhiro Yasunaga;Hitoshi Kaneko
• 通讯作者: Hitoshi Kaneko

名古屋大学脳とこころの研究センター・実際の応用研究紹介

名古屋大学脑与心智研究中心 - 实际应用研究介绍

heophanides T (Ed.) Infrared Spectroscopy - Life and Biomedical Sciences

heophanides T（主编）红外光谱 - 生命与生物医学科学

• 发表时间: 2012
• 作者: Kaneko H;Yoshikawa T;Ito H;Nomura K;Okada T & Honjo S
• 通讯作者: Okada T & Honjo S