Analysis of upstream and downstream signaling of IFITM3
Analysis of upstream and downstream signaling of IFITM3
批准号:
23790290
负责人:
NAKAJIMA Akira
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
Treatment with IFN-β、IL-1β, or TNF-α dose-dependently induced IFITM3 gene expression in cultured astrocytes. Pretreatment with helenalin,an NFκB inhibitor, had no effect on PolyI:C-induced IFITM3 gene epression. In contrast, PolyI:C-induced IFITM3 gene expression was significantly inhibited by pretreatment with BX795, a TBK-1 inhibitor. These results suggest that PolyI:C induces IFITM3 gene expression through TBK-1-IRF3 pathway in cultured astrocytes.
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培養アストログリア細胞におけるToll様受容体刺激は神経発達障害関連膜タンパク質IFITM3の発現を誘導する
刺激培养的星形胶质细胞中的 Toll 样受体可诱导神经发育障碍相关膜蛋白 IFITM3 的表达
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[中島晶, 衣斐大祐, 永井拓, 鍋島俊隆, 山田清文]
通讯作者:
山田清文
DOI:
10.1002/glia.22461
发表时间:
2013-05-01
期刊:
GLIA
影响因子:
6.2
作者:
[Ibi, Daisuke, Nagai, Taku, Yamada, Kiyofumi]
通讯作者:
Yamada, Kiyofumi
神経発達障害に関連する膜タンパク質IFITM3のTLRリガンドによる発現誘導
TLR 配体诱导 IFITM3(一种与神经发育障碍相关的膜蛋白)的表达
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Iesato Y, Tanaka M, et al., 中島晶ら]
通讯作者:
中島晶ら
培養アストログリア細胞における Toll 様受容体刺激は神経発達障害関連膜タンパク質IFITM3 の発現を誘導する
刺激培养的星形胶质细胞中的 Toll 样受体可诱导神经发育障碍相关膜蛋白 IFITM3 的表达
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[D Ibi, I Nagai, A Nakajima, H Mizoguchi, T Kawase, D Tsuboi, S Kano, Y Sato, M Hayakawa, U. C. Lange, D. J. Adams, M. Azim Surani, T Satoh, A Sawa, K Kaibuchi, T Nabeshima and K Yamada, 中島晶ら]
通讯作者:
中島晶ら
development of new system for energy recovery on Low-temperature waste heat using Leidenfrost phenomena
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批准号:18K19125
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
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资助金额:$4.08万
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财政年份:2018
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负责人:NAKAJIMA Akira
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依托单位:
Identification for TGF-beta signaling pathway in palatogenesis
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批准号:26463100
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.16万
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财政年份:2014
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负责人:NAKAJIMA Akira
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依托单位:
Mechanisms by which synthetic cathinones induce neurotoxicity
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批准号:26460625
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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财政年份:2014
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负责人:NAKAJIMA Akira
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Effects of water vapor treatment for the wettability conversion to hydrophobicity on the surface of oxide materials
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批准号:24360272
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.56万
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财政年份:2012
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负责人:NAKAJIMA Akira
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Investigation of the dew condensation and subsequent spontaneous jumping of droplets on the highly hydrophobic surface under cooling
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批准号:24655117
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.66万
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财政年份:2012
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负责人:NAKAJIMA Akira
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依托单位:
Identification of TGF-beta signaling during palatal fusion
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批准号:23593046
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2011
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负责人:NAKAJIMA Akira
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依托单位:
Investigation of the effects of surface water film and hierarchical solid texture on the hydrophilicity of ceramics surface
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批准号:21360317
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.48万
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财政年份:2009
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负责人:NAKAJIMA Akira
-
依托单位:
Analysis of functional significance of a newly discovered brain-specific transporter
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批准号:20390044
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.56万
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财政年份:2008
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负责人:NAKAJIMA Akira
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依托单位:
Identification for TGF-beta signaling during palatal development
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批准号:20592415
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2008
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负责人:NAKAJIMA Akira
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依托单位:
Development of Surface Functional Materials based on the Flow Dynamics at Solid Liquid Interface
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批准号:19350066
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.4万
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财政年份:2007
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负责人:NAKAJIMA Akira
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依托单位:
Biocontrol of reactive oxygen species produced by uranium and the analysis of chemical toxicity of depleted uranium.
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批准号:16510038
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.5万
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财政年份:2004
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负责人:NAKAJIMA Akira
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依托单位:
Study on measurement of three dimensional ball motion and running performance in rolling contact ball bearing under extremely high speed conditions
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批准号:14350082
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.82万
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财政年份:2002
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负责人:NAKAJIMA Akira
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依托单位:
Formation of reactive oxygen species in actinoide-including system and their bio-control
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批准号:13680592
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2001
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负责人:NAKAJIMA Akira
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依托单位:
Development of new adsorbents for heavy metals using microorganisms and their microcharacterization.
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批准号:10450393
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$7.42万
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财政年份:1998
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负责人:NAKAJIMA Akira
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依托单位:
Study on the heavy metal accumulation by biomass, and the developmernt of new adsorbents for heavy metals utilizing bio-accumulation mechanism.
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批准号:07651152
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.34万
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财政年份:1995
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负责人:NAKAJIMA Akira
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依托单位:
Basic and clinical research of YAG laser in ophthalmology was carried out
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批准号:58870085
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项目类别:Grant-in-Aid for Developmental Scientific Research
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资助金额:$5.76万
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财政年份:1983
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负责人:NAKAJIMA Akira
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依托单位:
海外基金