Influences of exercise, obesity and aging on growth hormone secretion and clarification of mechanism

运动、肥胖和衰老对生长激素分泌的影响及其机制的阐明

• 批准号: 23680063
• 负责人: GOTO Kazushige
• 金额: $ 17.56万
• 依托单位: Ritsumeikan University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (A)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23680063/
• 关键词: 成長ホルモン; 体脂肪; 内臓脂肪; 異所性脂肪; 低酸素; 有酸素運動; 生活習慣病

The present study investigated that influences of long-term exercise training and diet intervention on growth hormone secretions. The results from each experiment indicated that 2-4 weeks of exercise training and several days of diet intervention (increase in fat consumption) did not affect exercise-induced growth hormone response. However, exercise-induced growth hormone was significantly enhanced when the 4 week of exercise training was conducted in hypoxia. These findings suggest that exercise-induced growth hormone response is relatively robust under general situation. On the other hand, the findings newly suggest possibility that exercise-induced growth hormone response might be improved by exercise intervention with specific condition, such as the use of exposure to hypoxia during exercise.

本研究探讨了长期运动训练和饮食干预对生长激素分泌的影响。每个实验的结果表明，2-4周的运动训练和几天的饮食干预(增加脂肪消耗)不会影响运动诱导的生长激素反应。而在低氧条件下进行4周运动训练后，运动诱导的生长激素水平显著升高。这些发现表明，在一般情况下，运动诱导的生长激素反应相对较强。另一方面，新的发现表明，在特定条件下进行运动干预可能会改善运动诱导的生长激素反应，例如在运动期间暴露在低氧环境中。

项目成果

Effect of different periods of hypoxic training on glucose metabolism and insulin sensitivity

不同时期低氧训练对糖代谢及胰岛素敏感性的影响

• 发表时间: 2014
• 期刊: Clinical Physiology and Functional Imaging
• 影响因子: 1.8
• 作者: Morishima T;Hasegawa Y;Sasaki H;Kurihara T;Hamaoka T;Goto K
• 通讯作者: Goto K

Influence of high-intensity aerobic training on exercise-induced growth hormone response, abdominal and ectopic fat

高强度有氧训练对运动诱发的生长激素反应、腹部脂肪和异位脂肪的影响

• 发表时间: 2013
• 作者: Sasaki H;Morishima T;Hasegawa Y;Mori A;Ijichi T;Kurihara T;Goto K
• 通讯作者: Goto K

低酸素環境下での運動トレーニングが代謝・内分泌応答に及ぼす影響

低氧环境下运动训练对代谢和内分泌反应的影响

• 发表时间: 2013
• 作者: R.Furukawa;Y.Yamada;et al.;Yukio Nishimura;河野 史倫;後藤一成
• 通讯作者: 後藤一成

筋力トレーニングに対する代謝, 内分泌,および運動パフォーマンスの応答

代谢、内分泌和运动表现对力量训练的反应

• 发表时间: 2011
• 作者: 上田憲嗣;大友智;南島永衣子;梅垣明美;深田直宏;吉井健人;入江寿弘;喜多村麻里・有川秀之;後藤 一成
• 通讯作者: 後藤 一成

Effects of hypoxia exposure on metabolic response and endocrine regulation

缺氧对代谢反应和内分泌调节的影响

• 作者: Kinugawa S;Hirabayashi K;Suga T;Takahashi M;Takada S;Yokota T;Okita K;Tsutsui H.;内田千代子;沖田孝一;Kazushige Goto
• 通讯作者: Kazushige Goto