Study on the role of endoplasmic reticulum stress in the development of pancreatitis and new treatment through its amelioration

内质网应激在胰腺炎发生发展中的作用及改善其新疗法的研究

• 批准号: 24591021
• 负责人: AKIYOSHI NISHIO
• 金额: $ 3.33万
• 依托单位: Kansai Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24591021/
• 关键词: 膵炎; 小胞体ストレス; アポトーシス; セルレイン; エンドトキシン; 急性膵炎

项目成果

Amelioration of endoplasmic reticulum stress through enhanced PERK signaling attenuates murine experimental colitis

通过增强 PERK 信号传导改善内质网应激可减轻小鼠实验性结肠炎

• 作者: Kimi Sumimoto;Kazushige Uchida;Toshiyuki Mitsuyama;Yuri Fukui;Takeo Kusuda;Hideaki Miyoshi;Norimasa Fukata;Masanori Koyabu;Yutaku Sakaguchi;Tsukasa Ikeura;Masaaki Shimatani;Toshiro Fukui;Mitsunobu Matsushita;Makoto Takaoka;AkiyoshiNishio;Ka;Takashi Okazaki;Takashi Okazaki;Takashi Okazaki;Takashi Okazaki
• 通讯作者: Takashi Okazaki

Phosphorylation of Smad2/3 at Specific Linker Threonine Indicates Slow-Cycling Intestinal Stem-Like Cells Before Reentry to Cell Cycle

• DOI: 10.1007/s10620-014-3348-3
• 发表时间: 2015-02-01
• 期刊: DIGESTIVE DISEASES AND SCIENCES
• 影响因子: 3.1
• 作者: Kishimoto, Masanobu;Fukui, Toshiro;Okazaki, Kazuichi
• 通讯作者: Okazaki, Kazuichi

Comparison of International Consensus Diagnostic Criteria and Major Diagnostic Criteria for Autoimmune Pancreatitis

自身免疫性胰腺炎国际共识诊断标准与主要诊断标准比较

• 发表时间: 2012
• 作者: Sumimoto ;Uchida K;Fukui K;Kusuda ;Hideaki Miyoshi;Norimasa Fukata;Masanori Koyabu;Yutaku Sakaguchi;Tsukasa Ikeura;Masaaki Shimatani;Toshiro Fukui;Mitsunobu Matsushita;Makoto Takaoka;Akiyoshi Nishio;Okazaki K
• 通讯作者: Okazaki K

Immunoregulatory function of PIR-A/B+ DCs in the inflammatory responses of dextran sodium sulfate-induced colitis

PIR-A/B DCs在右旋糖酐硫酸钠诱导的结肠炎炎症反应中的免疫调节功能

• DOI: 10.1007/s00535-013-0879-x
• 发表时间: 2014
• 期刊: Journal of Gastroenterology
• 影响因子: 6.3
• 作者: Kurishima A;Inaba M;Sakaguchi Y;Fukui T;Uchida K;Nishio A;Nomura S;Okazaki K
• 通讯作者: Okazaki K

Possible involvement of Toll-like receptor 7 in the development of type 1 autoimmune pancreatitis

• DOI: 10.1007/s00535-014-0977-4
• 发表时间: 2015-04-01
• 期刊: JOURNAL OF GASTROENTEROLOGY
• 影响因子: 6.3
• 作者: Fukui, Yuri;Uchida, Kazushige;Okazaki, Kazuichi
• 通讯作者: Okazaki, Kazuichi