Development of novel thymus-directed strategy for central immune tolerance induction in hemophilia A
Development of novel thymus-directed strategy for central immune tolerance induction in hemophilia A
批准号:
24591430
负责人:
MADOIWA Seiji
金额:
$3.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2015-03-31
中文摘要
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Regulation of plasminogen activator inhibitor-1 promotes immune tolerance to factor VIII in murine hemophilia A
纤溶酶原激活剂抑制剂-1的调节促进小鼠血友病A对因子VIII的免疫耐受
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Madoiwa S, Ohmori T, Kashiwakura Y, Sakata A, Mimuro J, Sakata Y]
通讯作者:
Sakata Y
Lack of association between serum paraoxonase-1 activity and residual platelet aggregation during dual anti-platelet therapy
双抗血小板治疗期间血清对氧磷酶-1 活性与残留血小板聚集之间缺乏关联
DOI:
10.1016/j.thromres.2011.10.033
发表时间:
2012
期刊:
Thromb Res
影响因子:
7.5
作者:
[Ohmori, T., et al.]
通讯作者:
et al.
DOI:
10.1016/j.ajpath.2011.12.012
发表时间:
2012-04-01
期刊:
AMERICAN JOURNAL OF PATHOLOGY
影响因子:
6
作者:
[Norimatsu, Yusuke, Ohmori, Tsukasa, Sakata, Yoichi]
通讯作者:
Sakata, Yoichi
DOI:
10.1111/j.1365-2516.2011.02686.x
发表时间:
2012-05-01
期刊:
HAEMOPHILIA
影响因子:
3.9
作者:
[Madoiwa, S., Kobayashi, E., Sakata, Y.]
通讯作者:
Sakata, Y.
Combination of thrombin-antithrombin complex, plasminogen activator inhibitor-1, and protein C activity for early identification of severe coagulopathy in initial phase of sepsis: a prospective observational study.
凝血酶 - 抗凝结蛋白复合物,纤溶酶原激活剂-1和蛋白C活性的结合,可在败血症的初始阶段早期鉴定出严重的凝血病:一项前瞻性观察性研究。
DOI:
10.1186/cc13190
发表时间:
2014-01-13
期刊:
Critical care (London, England)
影响因子:
--
作者:
[Koyama K, Madoiwa S, Nunomiya S, Koinuma T, Wada M, Sakata A, Ohmori T, Mimuro J, Sakata Y]
通讯作者:
Sakata Y
共 21 条
Regulation of plasminogen activator inhibitor-1 promotes the immune response to factor VIII in murine hemophilia A.
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批准号:21591249
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2009
-
负责人:MADOIWA Seiji
-
依托单位:
Development of immune-tolerance induction by continuous infusion of FactorVIII using micro-injection system in murine hemophilia A
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批准号:19591133
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2007
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负责人:MADOIWA Seiji
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依托单位:
Induction of factor VIII specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A
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批准号:17591006
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2005
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负责人:MADOIWA Seiji
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依托单位:
Induction of Immune Tolerance by Neonatal Intravenous Injection of Human Factor VIII in Murine Hemophilia A
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批准号:15591021
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2003
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负责人:MADOIWA Seiji
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依托单位:
Gene therapy for hemophilia A with simian immunodeficiency virus agmTYO1-based vectors carrying human factor VIII gene.
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批准号:13671078
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.86万
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财政年份:2001
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负责人:MADOIWA Seiji
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依托单位:
海外基金