Development of hybrid screening system for barrier-disrupted and immune-activated substance

提示过敏等免疫性疾病与上皮细胞屏障破坏有关。在本研究中，我们为开发同时评估屏障功能和环境污染免疫反应的杂交检测系统提供了基础数据。观察到各种环境污染物都降低了屏障功能，扰乱了免疫反应。这些结果表明，开发一种可以同时评估环境污染对机体屏障功能和免疫反应的混合检测系统是可能的。

It is suggested that the immune diseases such as allergies causes it with the disruption of epithelial cell barrier. In this study, we performed the basic data for development of the hybrid detection system that could evaluate the barrier function and the immune response by an environmental pollution at the same time. It was observed that various environmental pollutants were decreased barrier function, and disrupted the immune response. There results suggest the possibility to develop the hybrid detection system that could evaluate the barrier function and the immune response by an environmental pollution at the same time.