Development of novel biomaterial using poly(P) and bFGF onto porous hydroxyl apatite
使用聚(P)和bFGF在多孔羟基磷灰石上开发新型生物材料
基本信息
- 批准号:24792143
- 负责人:
- 金额:$ 2.75万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Young Scientists (B)
- 财政年份:2012
- 资助国家:日本
- 起止时间:2012-04-01 至 2014-03-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
In difficult situation of bone augmentation such as horizontality bone regeneration, development of newly habrized biomaterials with bone formation promoting effective is demanded. we determined the optimum chain length of poly(P) binding to bFGF, we developed a composite of poly(P) and bFGF with IP-CHA as an innovative artificial bone for predictable bone regeneration. that in vitro study, poly(P) and bFGF promote osteoblast activities as interaction efforts. Also in vivo study, poly(P) and b FGF combined onto IP-CHA were established promoted bone formation.
在水平骨再生等骨增强困难的情况下,需要开发能有效促进骨形成的新型仿生材料。我们确定了聚(P)与bFGF结合的最佳链长,我们开发了聚(P)和bFGF与IP-CHA的复合材料,作为可预测的骨再生的创新人工骨。体外研究表明,聚(P)和bFGF通过相互作用促进成骨细胞活性。体内实验也证实poly(P)和b FGF与IP-CHA结合可促进骨形成。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Influence of formalin fixation on implant stability quotient and bone mechanical characteristics
福尔马林固定对种植体稳定性商和骨力学特性的影响
- DOI:
- 发表时间:2012
- 期刊:
- 影响因子:0
- 作者:Morita K;DOI: K;Oue H;Kajihara S;Hayashi K;Akagawa Y
- 通讯作者:Akagawa Y
Influence of formalin fixation on the implant stability quotient and mechanical characteristics of bone
- DOI:10.1016/j.bjoms.2012.08.009
- 发表时间:2013-09-01
- 期刊:
- 影响因子:1.8
- 作者:Morita, Koji;Doi, Kazuya;Akagawa, Yasumasa
- 通讯作者:Akagawa, Yasumasa
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HAYASHI Kazuhiko其他文献
Feasibility of carbon-ion radiotherapy for oral non-squamous cell carcinomas
碳离子放射治疗口腔非鳞状细胞癌的可行性
- DOI:
10.5794/jjoms.67.100 - 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
IKAWA Hiroaki;KOTO Masashi;HAYASHI Kazuhiko;TONOGI Morio;TAKAGI Ryo;NOMURA Takeshi;TSUJI Hiroshi;KAMADA Tadashi - 通讯作者:
KAMADA Tadashi
HAYASHI Kazuhiko的其他文献
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{{ truncateString('HAYASHI Kazuhiko', 18)}}的其他基金
Establishment of MCPyV-infection experimental system and the therapy base on the carcinogenesis of MCPyV-positive Merkel cell carcinoma
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25820202 - 财政年份:2013
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$ 2.75万 - 项目类别:
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Pathological analysis of chronic active EBV-infection rabbit model with hemophagocytosis
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$ 2.75万 - 项目类别:
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使用 rh-BMP-2-明胶水凝胶复合物开发新型植入增强药物输送系统
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22791886 - 财政年份:2010
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$ 2.75万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Research of the characteristics of disseminated gastric cancer cells and the factors of sensitivity and tolerance to chemotherapeutic agents.
播散性胃癌细胞特性及化疗药物敏感性、耐受性因素研究。
- 批准号:
21591713 - 财政年份:2009
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Influencing factors affecting steel corrosion of concrete members subjected to fatigue loading
疲劳荷载下混凝土构件钢材腐蚀的影响因素
- 批准号:
21760351 - 财政年份:2009
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$ 2.75万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Synthesis and Reaction of Strained Azabicyclic Compounds
应变氮杂双环化合物的合成与反应
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20550102 - 财政年份:2008
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$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
The first animal model for "Hit and Run" theory of oncogenesis by EBV related virus
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- 批准号:
16590314 - 财政年份:2004
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Analysis of speciation process in Liliaceae sensu lato
百合科物种形成过程分析
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14540652 - 财政年份:2002
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Pathological analyses and therapeutic trials of animal model of EB virus-related fatal hemophagocytic syndrome
EB病毒相关致死性噬血细胞综合征动物模型的病理分析及治疗试验
- 批准号:
14570190 - 财政年份:2002
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
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