Development of New Implant Augmentation Drug Delivery System Using a rh-BMP-2-Gelatin Hydrogel Complex
Development of New Implant Augmentation Drug Delivery System Using a rh-BMP-2-Gelatin Hydrogel Complex
批准号:
22791886
负责人:
HAYASHI Kazuhiko
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
采用兔顶骨骨缺损模型,明确了rh-BMP-2在明胶复合物中的最佳剂量。将复合物移植到杂交犬的骨缺损模型中。观察期结束后,取出组织块,制作标本并进行组织学观察。观察骨缺损内再生的骨组织。rh-BMP-2用量越大,骨面积率越大。
英文摘要
Optimum dose of rh-BMP-2in gelatin complex was clarified using the bone deficit model of the rabbit parietal bone. The complex was transplanted to the bone deficit model of a hybrid dog. After the observation period, the organization block was extracted, and the specimen was produced and was observed histologically. The bone tissue reproduced inside the bone deficit was observed. When rh-BMP-2quantity became large, the rate of bone area became large.
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专著(0)
科研奖励(0)
会议论文
Development of implant/ interconnected porous calciumhyd roxyapatite complex
植入物/互连多孔羟基磷灰石复合物的开发
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[H. Oue, K. Doi, T. Kubo, K. Koretake, K. Hayashi, S. Kajihara, K. Imura and Y. Akagawa]
通讯作者:
K. Imura and Y. Akagawa
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Masuzaki, Ayukawa, Koyano, ら, Hiroshi Oue et al]
通讯作者:
Hiroshi Oue et al
インターナルジョイント型インプラントを用いた臨床予後
使用内关节型植入物的临床预后
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[林和彦, 日浅恭, 阿部泰彦, 久保隆靖, 赤川安正]
通讯作者:
赤川安正
Establishment of MCPyV-infection experimental system and the therapy base on the carcinogenesis of MCPyV-positive Merkel cell carcinoma
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批准号:17K08720
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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负责人:HAYASHI Kazuhiko
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依托单位:
Development of methods for quality evaluation of actual concrete structures by surface water absorption test
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依托单位:
Development of novel biomaterial using poly(P) and bFGF onto porous hydroxyl apatite
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批准号:24792143
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财政年份:2012
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依托单位:
Pathological analysis of chronic active EBV-infection rabbit model with hemophagocytosis
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批准号:23590463
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资助金额:$3.24万
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财政年份:2011
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依托单位:
Research of the characteristics of disseminated gastric cancer cells and the factors of sensitivity and tolerance to chemotherapeutic agents.
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批准号:21591713
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2009
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负责人:HAYASHI Kazuhiko
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依托单位:
Influencing factors affecting steel corrosion of concrete members subjected to fatigue loading
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批准号:21760351
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资助金额:$2.5万
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财政年份:2009
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负责人:HAYASHI Kazuhiko
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Synthesis and Reaction of Strained Azabicyclic Compounds
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批准号:20550102
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资助金额:$3.33万
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财政年份:2008
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负责人:HAYASHI Kazuhiko
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依托单位:
The first animal model for "Hit and Run" theory of oncogenesis by EBV related virus
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批准号:16590314
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2004
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负责人:HAYASHI Kazuhiko
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依托单位:
Analysis of speciation process in Liliaceae sensu lato
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批准号:14540652
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2002
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负责人:HAYASHI Kazuhiko
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依托单位:
Pathological analyses and therapeutic trials of animal model of EB virus-related fatal hemophagocytic syndrome
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批准号:14570190
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2002
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负责人:HAYASHI Kazuhiko
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依托单位:
ANIMAL MODEL FOR HUMAN EB VIRUS-RELATED TUMOR: PATHOGENESIS OF RABBIT LYMPHOMA INDUCED BY SIMIAN EBV-RELATED VIRUS
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批准号:11470058
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.02万
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财政年份:1999
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负责人:HAYASHI Kazuhiko
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依托单位:
T cell clonality of TIL (tumor-infiltrating lymphocytes) and PBL in vivo, and analysis of tumor-specific T cell clonotype
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批准号:07671832
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项目类别:Grant-in-Aid for Scientific Research (C)
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负责人:HAYASHI Kazuhiko
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依托单位:
海外基金