Identification of novel differentiation factors in immune system using iPS cells derived from primary immunodeficiencies.

使用源自原发性免疫缺陷的 iPS 细胞鉴定免疫系统中的新型分化因子。

• 批准号: 26293250
• 负责人: NONOYAMA Shigeaki
• 金额: $ 10.57万
• 依托单位: National Defense Medical College
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2014
• 资助国家: 日本
• 起止时间: 2014-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26293250/
• 关键词: 免疫学; 発生・分化; 移植・再生医療; 細胞・組織; 遺伝子

项目成果

Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency.

• DOI: 10.3389/fimmu.2011.00054
• 发表时间: 2011
• 期刊: Frontiers in immunology
• 影响因子: 7.3
• 作者: Al-Herz W;Bousfiha A;Casanova JL;Chapel H;Conley ME;Cunningham-Rundles C;Etzioni A;Fischer A;Franco JL;Geha RS;Hammarström L;Nonoyama S;Notarangelo LD;Ochs HD;Puck JM;Roifman CM;Seger R;Tang ML
• 通讯作者: Tang ML

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome.

• DOI: 10.1084/jem.20140280
• 发表时间: 2015-09-21
• 期刊: The Journal of experimental medicine
• 作者: Kreins AY;Ciancanelli MJ;Okada S;Kong XF;Ramírez-Alejo N;Kilic SS;El Baghdadi J;Nonoyama S;Mahdaviani SA;Ailal F;Bousfiha A;Mansouri D;Nievas E;Ma CS;Rao G;Bernasconi A;Sun Kuehn H;Niemela J;Stoddard J;Deveau P;Cobat A;El Azbaoui S;Sabri A;Lim CK;Sundin M;Avery DT;Halwani R;Grant AV;Boisson B;Bogunovic D;Itan Y;Moncada-Velez M;Martinez-Barricarte R;Migaud M;Deswarte C;Alsina L;Kotlarz D;Klein C;Muller-Fleckenstein I;Fleckenstein B;Cormier-Daire V;Rose-John S;Picard C;Hammarstrom L;Puel A;Al-Muhsen S;Abel L;Chaussabel D;Rosenzweig SD;Minegishi Y;Tangye SG;Bustamante J;Casanova JL;Boisson-Dupuis S
• 通讯作者: Boisson-Dupuis S

Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies.

• DOI: 10.1016/j.jaci.2015.05.036
• 发表时间: 2015-10
• 期刊: The Journal of allergy and clinical immunology
• 作者: Ma CS;Wong N;Rao G;Avery DT;Torpy J;Hambridge T;Bustamante J;Okada S;Stoddard JL;Deenick EK;Pelham SJ;Payne K;Boisson-Dupuis S;Puel A;Kobayashi M;Arkwright PD;Kilic SS;El Baghdadi J;Nonoyama S;Minegishi Y;Mahdaviani SA;Mansouri D;Bousfiha A;Blincoe AK;French MA;Hsu P;Campbell DE;Stormon MO;Wong M;Adelstein S;Smart JM;Fulcher DA;Cook MC;Phan TG;Stepensky P;Boztug K;Kansu A;İkincioğullari A;Baumann U;Beier R;Roscioli T;Ziegler JB;Gray P;Picard C;Grimbacher B;Warnatz K;Holland SM;Casanova JL;Uzel G;Tangye SG
• 通讯作者: Tangye SG

International Consensus Document (ICON): Common Variable Immunodeficiency Disorders.

• DOI: 10.1016/j.jaip.2015.07.025
• 发表时间: 2016-01
• 期刊: The journal of allergy and clinical immunology. In practice
• 作者: Bonilla FA;Barlan I;Chapel H;Costa-Carvalho BT;Cunningham-Rundles C;de la Morena MT;Espinosa-Rosales FJ;Hammarström L;Nonoyama S;Quinti I;Routes JM;Tang ML;Warnatz K
• 通讯作者: Warnatz K

Analysis of somatic hypermutation in the IgM switch region in human B cells.

人类 B 细胞 IgM 开关区域体细胞超突变分析。

• DOI: 10.1016/j.jaci.2014.02.043
• 发表时间: 2014
• 期刊: J Allergy Clin Immunol.
• 作者: Michiyo Nakano;Noriaki Kamada;Ayako Oikawa;Chihori Shibata;Yusuke Sasahara;Hiroyuki Hosokawa;Toshinori Nakayama;Ken Nonaka;Osamu Ohara;Yuumi Nakamura and Hiroyuki Matsue.;森尾友宏;Horiuchi K
• 通讯作者: Horiuchi K