Establishment of molecular basis of CCN family proteins for therapeutic use and its related translational research
Establishment of molecular basis of CCN family proteins for therapeutic use and its related translational research
批准号:
15H05014
负责人:
TAKIGAWA Masaharu
金额:
$10.9万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2015
资助国家:
日本
项目状态:
已结题
起止时间:
2015-04-01 至 2018-03-31
中文摘要
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英文摘要
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DOI:
10.1371/journal.pone.0188014
发表时间:
2017
期刊:
PloS one
影响因子:
3.7
作者:
[Hori A, Nishida T, Takashiba S, Kubota S, Takigawa M]
通讯作者:
Takigawa M
Mechanism of the catabolic effects of Fibroblast Growth Factor (FGF-1) on chondrocytes and its possible role in Osteoarthritis
成纤维细胞生长因子(FGF-1)对软骨细胞的分解代谢作用机制及其在骨关节炎中的可能作用
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[Elseoudi, A., Abd El Kader, T., Nishida T., Aoyama, E., Eguchi, T., Takigawa, M., Kubota, S.]
通讯作者:
S.
Generation and Analysis of Cartilage-Specific CCN2 Overexpression in Transgenic Mice.
转基因小鼠中软骨特异性 CCN2 过表达的生成和分析。
DOI:
10.1007/978-1-4939-6430-7_32
发表时间:
2016
期刊:
Methods Mol Biol.
影响因子:
--
作者:
[Hattori T, Itoh S, and Takigawa M]
通讯作者:
and Takigawa M
Ccn4欠損マウスを用いた関節軟骨創傷治癒におけるCCN4の役割の解明
使用 Ccn4 缺陷小鼠阐明 CCN4 在关节软骨伤口愈合中的作用
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[吉岡裕也、大野充昭、前田あずさ、Hara, E. S., 植田淳二、青山絵理子、滝川正春、大橋俊孝、Young, M. F., 窪木拓男]
通讯作者:
窪木拓男
CCN Proteins: Methods and Protocols (one of the "Methods in Molecular Biology" book series)
CCN 蛋白质:方法和方案(“分子生物学方法”系列丛书之一)
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[Yamada Y, Ohazama A, Maeda T, Seo K, Takigawa M.(ed)]
通讯作者:
Takigawa M.(ed)
共 141 条
Neutrigenomics studies on endochondral ossification and articular cartilage mainteinance/regeneration
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批准号:17K19757
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
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资助金额:$4.16万
-
财政年份:2017
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负责人:TAKIGAWA Masaharu
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依托单位:
A new protein transport system in cartilage: Multilayered transcytosis
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批准号:23659872
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2011
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负责人:TAKIGAWA Masaharu
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依托单位:
Comprehensive study on molecular basis of actions of CCN family proteins as novel signal conductors and its translational application
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批准号:19109008
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$70.72万
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财政年份:2007
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负责人:TAKIGAWA Masaharu
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依托单位:
The role of CTGF as a novel tissue-regenerating factor, regenerin, and its application for medical and dental tissue engineering
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批准号:15109010
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$66.48万
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财政年份:2003
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负责人:TAKIGAWA Masaharu
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依托单位:
Functional analysis of the cartilage-derived multifunctional growth factor ecogenin/CTGF by using mutant animals
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批准号:13307053
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$23.71万
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财政年份:2001
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负责人:TAKIGAWA Masaharu
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依托单位:
Development of analytical method for each domain of CTGF/ecogenin and its clinical application.
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批准号:12557154
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.45万
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财政年份:2000
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负责人:TAKIGAWA Masaharu
-
依托单位:
Studies on the mechanism of actions of a cartilage-derived pleiotrophic growth factor, ecogenin/CTGF - Molecular cloning of its receptors and mechanism of inter- and intra signal transduction -
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批准号:10470389
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$8.51万
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财政年份:1998
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负责人:TAKIGAWA Masaharu
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依托单位:
Development of inhibitors for a angiogenesis factor CTGF and its application for angiogenetic diseases
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批准号:10557165
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.77万
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财政年份:1998
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负责人:TAKIGAWA Masaharu
-
依托单位:
The role of hcs-24, a newly isolated hypertrophic chondrocyte-specific gene, in endochondral ossification
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批准号:08457490
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$1.22万
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财政年份:1996
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负责人:TAKIGAWA Masaharu
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依托单位:
Molecular cloning of novel osteoneurotrophins and their application as therapeutic agents for bone and cartilage diseases
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批准号:08557098
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$12.86万
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财政年份:1996
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负责人:TAKIGAWA Masaharu
-
依托单位:
Cloning and functional analysis of novel genes related to chondrocyte differentiation using the human chondrocytic cell lines
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批准号:06454521
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.54万
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财政年份:1994
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负责人:TAKIGAWA Masaharu
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依托单位:
Studies on the mechanism of endochondral ossification using a clonal chondrocyte like cell line newly established from a human chondrosarcoma - approach using the methods of cellular and molecular biology
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批准号:03454429
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$3.84万
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财政年份:1991
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负责人:TAKIGAWA Masaharu
-
依托单位:
Studies on mechanisms of proliferation, differentiation and calcification of chondrocytes using established clonal cell lines.
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批准号:63480411
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.16万
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财政年份:1988
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负责人:TAKIGAWA Masaharu
-
依托单位:
Purification of cartilage-derived anti-tumor factor (CATF) and establishment of cell lines which produce CATF
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批准号:61480387
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.16万
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财政年份:1986
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负责人:TAKIGAWA Masaharu
-
依托单位:
Bioassays for parathyrois hormone using clutures chondrocytes
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批准号:60870013
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项目类别:Grant-in-Aid for Developmental Scientific Research
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资助金额:$2.43万
-
财政年份:1985
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负责人:TAKIGAWA Masaharu
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依托单位:
海外基金