Elucidation of recognition mechanisms of fatty acids and their related substances by class B scavenger receptors

阐明B类清道夫受体对脂肪酸及其相关物质的识别机制

• 批准号: 16K07733
• 负责人: TSUZUKI SATOSHI
• 金额: $ 3万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-10-21 至 2019-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K07733/
• 关键词: クラスBスカベンジャー受容体; 長鎖脂肪酸; 酸化型リポ蛋白質; 酸化型リン脂質; CD36; 脂肪族アルデヒド; 嗅上皮; 酸化型リポタンパク質; SR-B1; 酸化型リポタンパク室; SR-BI; 生体分子; 食品; 脂質; 蛋白質; 動物

项目成果

A Search for CD36 Ligands from Flavor Volatiles in Foods with an Aldehyde Moiety: Identification of Saturated Aliphatic Aldehydes with 9-16 Carbon Atoms as Potential Ligands of the Receptor.

从含有醛部分的食品中的风味挥发物中寻找 CD36 配体：鉴定具有 9-16 个碳原子的饱和脂肪醛作为受体的潜在配体。

• DOI: 10.1021/acs.jafc.7b01890
• 发表时间: 2017
• 期刊: Journal of Agricultural and Food Chemistry
• 影响因子: 6.1
• 作者: Tsuzuki S;Amitsuka T;Okahashi T;Kimoto Y;Inoue K
• 通讯作者: Inoue K

CD36 involvement in the olfactory perception of oleic aldehyde, an odour-active volatile compound, in mice

• DOI: 10.2220/biomedres.38.207
• 发表时间: 2017-01-01
• 期刊: BIOMEDICAL RESEARCH-TOKYO
• 影响因子: 1.2
• 作者: Lee, Shinhye;Tsuzuki, Satoshi;Inoue, Kazuo
• 通讯作者: Inoue, Kazuo

A role for scavenger receptor B1 as a captor of specific fatty acids in taste buds of circumvallate papillae.

清道夫受体 B1 作为周围乳头味蕾中特定脂肪酸的捕获者的作用。

• 发表时间: 2018
• 期刊: Biomedical Research
• 作者: Tsuzuki S;Lee S;Kimoto Y;Sugawara T;Manabe Y;Inoue K
• 通讯作者: Inoue K

<b>Identification of the odor-active volatile compound (</b><i><b>Z</b></i><b>,</b><i><b>Z</b></i><b>)-4,7-tridecadienal as a potential ligand for the transmembrane receptor </b><b>CD36 </b>

<b>气味活性挥发性化合物的鉴定（</b><i><b>Z</b></i><b>，</b><i><b>Z</b>

• DOI: 10.2220/biomedres.37.335
• 发表时间: 2016
• 期刊: Biomedical Research
• 作者: Tsuzuki S;Amitsuka T;Okahashi T;Kozai Y;Yamasaki M;Inoue K;Fushiki T.
• 通讯作者: Fushiki T.

A novel role for scavenger receptor B1 as a contributor to the capture of specific volatile odorants in the nasal cavity.

清道夫受体 B1 的新作用是捕获鼻腔中特定的挥发性气味物质。

• DOI: 10.2220/biomedres.39.117
• 发表时间: 2018
• 期刊: Biomedical research
• 作者: S. Tsuzuki;Yusaku Kimoto;Shinhye Lee;T. Sugawara;Y. Manabe;Kazuo Inoue
• 通讯作者: Kazuo Inoue