Mandibular condyle bone mineral density measurement by quantitative computed tomography

定量计算机断层扫描测量下颌骨髁骨密度

• 批准号: 09671928
• 负责人: NAKAMURA Takashi
• 金额: $ 1.98万
• 依托单位: Nagasaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09671928/
• 关键词: mandibular condyle; bone mineral density; quantitative computed tomography; spine; age; gender; 骨髄; MRI; 下顎骨; 咬合力; ホルモン

We conducted volunteer studies to asses age-related changes of mandibular condyle bone mineral density (BMD) and its correlation to the spinal BMD.Quantitative computed tomography was performed on the condyles and spines (L1-3) of 210 healthy subjects (114 men and 96 women, aged 5-85 years). A separate study was performed on 73 young student subjects (39 men and 34 women, aged 23-25 years). The mandibular condyle BMD showed a decrement rate similar to spinal BMD in men, but in women the decrement rate similar to spinal BMD in men, but in women the decrement rate of the mandibular condyle BMD was lower than that of the LI-3 BMD.On the other hand, correlation coefficients in BMD between the mandibular condyle and spine were similar in women and men. Gender-refated differences were found to be dramatic when assessed in the young student group ; the mandibular condyle and spinal BMDs were highly correlated in women (r = 0.82, p < 0.0001), but no correlation was found in men (r = 0.22). Taken together, these results suggest that the same regulatory mechanisms exist in the mandibular condyle and spine BMDs. However, aside from the spine BMD, additional undefined factor(s), including mechanical stress from the occlusion, may be involved in maintaining mandibular BMD.

我们进行了志愿者研究，以评估下颌髁骨矿物质密度（BMD）的年龄相关变化及其与脊柱骨密度的相关性。对210名健康受试者（男性114名，女性96名，年龄5-85岁）的髁突和脊柱（L1-3）进行了定量计算机断层扫描。另一项独立研究对73名年轻学生（39名男性和34名女性，年龄在23-25岁）进行了研究。男性下颌髁骨密度的下降速率与脊柱骨密度相似，但女性骨密度的下降速率与男性脊柱骨密度相似，但女性下颌髁骨密度的下降速率低于LI-3骨密度。另一方面，女性和男性的骨密度与下颌髁和脊柱的相关系数相似。当对年轻学生群体进行评估时，发现与性别有关的差异是巨大的；女性下颌髁与脊柱骨密度高度相关（r = 0.82, p < 0.0001），而男性无相关性（r = 0.22）。综上所述，这些结果表明在下颌髁和脊柱骨密度中存在相同的调节机制。然而，除了脊柱骨密度外，其他未定义的因素，包括来自咬合的机械应力，可能参与维持下颌骨密度。

项目成果

T.Nakamura, et al: "Mandibular condyle BMD measurement by quantitative CT : A gender-related difference in correlation to the spinal BMD" Bone. 21. 441-445 (1997)

T.Nakamura 等人：“通过定量 CT 测量下颌骨髁 BMD：与脊柱 BMD 相关的性别差异” 骨。

T.Nakamura, et al: "Discrimination of spinal fracture with various bone mineral measurements." Calcif Tissue Int. 60. 11-15 (1997)

T.Nakamura 等人：“通过各种骨矿物质测量来区分脊柱骨折。”

T.Nakamura, 他7名: "Spinal trabecular bone loss and fracture in American and Japanese women" Calcif Tissue Int. 61. 128-128 (1997)

T. Nakamura 等 7 人：“美国和日本女性的脊柱小梁骨丢失和骨折”Calcif Tissue Int. 61. 128-128 (1997)

T.Nakamura,他5名: "Relationship of spinal fracture to bone density,textural,and anthropometric parameters" Calcif Tissue Int. 60. 240-243 (1997)

T. Nakamura 等 5 人：“脊柱骨折与骨密度、结构和人体测量参数的关系”Calcif Tissue Int. 60. 240-243 (1997)

T.Nakamura,他7名: "Spinal trabecular bone loss and fracture in American and Japanese women" Calcif Tissue Int. 61. 123-128 (1997)

T. Nakamura 等 7 人：“美国和日本女性的脊柱小梁骨丢失和骨折”Calcif Tissue Int. 61. 123-128 (1997)