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Development of bone cement with affinity bio-adhesion

Development of bone cement with affinity bio-adhesion
具有亲和性生物粘附力的骨水泥的研制
批准号:
09558119
负责人:
OKAZAKI Masayuki
金额:
$7.1万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
1997
资助国家:
日本
项目状态:
已结题
起止时间:
1997 至 1999

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项目成果

OKAZAKI Masayuki的其他基金

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中文摘要
翻译
Recent focus is to develop a bone cement with strong mechanical properties and good biocompatibility.We studied the physicochemical properties of various kind of synthetic apatites and the modification of functional polymers.According to the accumulated knowledge,at first we tried to synthesize functionally graded Mg-containing CO ei D23文件D2 apatites X-ray diffraction,electron spectroscopy for chemical analyses showed the Mg-containing CO锡D23文件D2 apatites had a negative gradient of Mg content from the surface toward the inner core of the crystal.The composites of the apatite and collagen showed rather higher mechanical properties and good biocompatibility,but the mechanical properties did not reach to those of bone。The investigation on hybrid bone cement of this composite and phosphoric ester monomer is in progress.
英文摘要
Recent focus is to develop a bone cement with strong mechanical properties and good biocompatibility. We studied the physicochemical properties of various kind of synthetic apatites and the modification of functional polymers. According to the accumulated knowledge, at first we tried to synthesize functionally graded Mg-containing COィイD23ィエD2 apatites X-ray diffraction, electron spectroscopy for chemical analyses showed the Mg-containing COィイD23ィエD2 apatites had a negative gradient of Mg content from the surface toward the inner core of the crystal. The composites of the apatite and collagen showed rather higher mechanical properties and good biocompatibility, but the mechanical properties did not reach to those of bone. The investigation on hybrid bone cement of this composite and phosphoric ester monomer is in progress.
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会议论文
Okazaki,M.: "Synthesis of functionally graded CO_3apatite as surface biodegradable crystals"Biomaterials. 20. 1073-1078 (1999)
冈崎,M.:“作为表面可生物降解晶体的功能分级CO_3磷灰石的合成”生物材料。
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通讯作者:
M.Okazaki: "Heterogeneous fluoridated apatites synthesized with a three-step fluoride supplly system" Biomaterials. 19. 919-923 (1998)
M.Okazaki:“用三步氟化物供应系统合成的异质氟化磷灰石”生物材料。
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通讯作者:
Nakahira,A.: "Novel synthesis mthod of hydroxyapatite whiskers by hydrolysis of α-tricalcium phosphate in mixtures of water and organic solvent"J Am Ceram Soc. 82. 2029-2032 (1999)
Nakahira, A.:“在水和有机溶剂的混合物中水解α-磷酸三钙合成羟基磷灰石晶须的新方法”J Am Ceram Soc. 82. 2029-2032 (1999)
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通讯作者:
Okazaki, M. and Takahashi, J.: "Synthesis of functionally graded COィイD23ィエD2 apatite as surface biodegradable crystals."Biomaterials. 20. 1073-1078 (1999)
Okazaki, M. 和 Takahashi, J.:“作为表面可生物降解晶体的功能分级 CO2 磷灰石的合成。”生物材料。 20. 1073-1078 (1999)
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通讯作者:
9
    Affinity chemical modification and functional control onto carbonate-apatite composite scaffolds
    • 批准号:
      18390515
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.95万
    • 财政年份:
      2006
    • 负责人:
      OKAZAKI Masayuki
    • 依托单位:
    Creation of high-quality COaAp-collagen composites for reconstruction and regeneration of alveolar bone
    • 批准号:
      14370634
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $6.72万
    • 财政年份:
      2002
    • 负责人:
      OKAZAKI Masayuki
    • 依托单位:
    Chemical Modification of Adhesion Motif onto Apatite-Collagen Laminated Composites
    • 批准号:
      11671928
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.18万
    • 财政年份:
      1999
    • 负责人:
      OKAZAKI Masayuki
    • 依托单位:
    Hybridization and Modification of Apatite-Collagen Composite Membranes
    • 批准号:
      08672233
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.41万
    • 财政年份:
      1996
    • 负责人:
      OKAZAKI Masayuki
    • 依托单位:
    国内基金
    海外基金
    里氏木霉纤维素酶cbh基因表达系统调控蛋白分析
    • 批准号:
      30670056
    • 项目类别:
      面上项目
    • 资助金额:
      30.0万元
    • 批准年份:
      2006
    • 负责人:
      董志扬
    • 依托单位: