Insolubilization and Adhesive Properties of Biomimetic Collagen asan Artificial Periodontal Membrane

最近，我们的社会正在进入老龄化社会。越来越多的人正在失去牙齿，必须使用人工假肢，如假牙和人工牙根。由于天然的牙周膜既能连接牙根和牙槽骨，又能吸收外力，因此开发一种优良的牙周膜修复材料并不容易。扫描电镜对牙周膜的观察清楚地显示出这种复杂的生物粘附。我们对人工牙周膜的研究结果表明，通过紫外线照射和等离子体处理，成功地实现了胶原蛋白的不溶化和与磷灰石-胶原复合物的粘附。然而，由于人工牙周膜-牙根系统的粘接强度和形状问题一直没有得到解决。进一步的调查正在进行中。

Recently, our society is growing into and aged society. More people are losing their teeth and must use artificial prothetics such as dentures and artificial tooth roots. It is not easy to develop an excellent restorative material for periodontal membrane because the natural periodontal membrane contributes to connect tooth root and alveolar bone, and also acts as a xhock absorber for exterior force. The observation of the periodontal mebrane using scanning electron mictoscope clearly showed such complicate bio-adhesion. As the results of our investigation concerning the artificial periodontal membrane, insolubilixation of collagen and its adhesion to apatite-collagen composites were successfully achieved by UV-ray irradiation and plasma treatment. However, since adhesive strength and shape problem of artificial periodontal membrane-tooth root system have not been resolved. further investigations are in progress.