Physiological Relevance of Intracellular Magnesium

在蒙布usho国际合作资助者期间，Nakayama Shinsuke（首席研究员）访问了牛津大学药理学系和生物化学系，牛津大学（从97年8月14日至97日）。Nakayama和调查者名单（Brading， A.）F.，Clark，J.F.，史密斯， L。M. M.） examined the effects of Mg D12+ Mg D1 on·brane currents in isolated smManagement muscle cells。此外，Nakayama在牛津逗留期间， Lorraine Smith发表了许多有用的评论，描述了手稿“内在Mgy D12+ Ye D1集中的荷尔蒙规则”。这本手稿已提交给一本科学期刊。关于另一手， Gail Pyne （研究员助理）访问名古屋大学医学院生理学系（表格97年6月27日至7月6日）。Gail Pyne started experiments regarding the interaction og Mg D12+イエD1 and spasminogen。Shinsuke Nakayama， Hideki Nomura和Kenji Kuba支持她的工作：在静态平滑肌肉中对氧消耗和张力的发展进行同样的测量。在实验中使用的Carotid Artery是由Motonobu Ohtsuki （名古屋Shokuniku中心）巧妙地提供的。盖尔·派恩继续在牛津生物化学系和英国神经外科研究小组第五届年会上的一些交流成果（Drymen， U.）K. K.在日本生理学会第75届年会上，“神经和肌肉生理学上的镁”专题讨论会在Kanazawa举行（3月98日）。In the symposium Shinsuke Nakayama communicated some of the results concerning hormonal regulation of intracellular MgイD12+イエD1。此外， Joseph Clark （调查员）和Peter Flatman （Lorraine Smith's前任主管：爱丁堡生理学部）也受到邀请。The titles of their communications were 'Magnesium in vas？smManagement muscle contraction' and 'Ion transporters and magnesium homeostasis"， respectively。

During the tenure of this Monbusho's international collaboration grant, Shinsuke Nakayama (Head Investigator) visited the Department of Pharmacology and the Department of Biochemistry, Oxford University, (from 14th August 97 to 17th September 97). Nakayama and the investigators listed (Brading, A. F., Clark, J. F., Smith, L. M. ) examined the effects of MgィイD12+ィエD1 on membrane currents in isolated smooth muscle cells. Also, during Nakayama was staying in Oxford, Lorraine Smith provided many useful comments on a manuscript describing 'Hormonal regulation of intracellular MgィイD12+ィエD1 concentration in heart'. This manuscript has been submitted to a scientific journal.On the other hand, Gail Pyne (Reserach Associate) visited the Department of Physiology, School of Medicine, Nagoya University (form 27th June 97 to 6th July 97). Gail Pyne started experiments regarding the interaction og MgィイD12+ィエD1 and spasminogen. Shinsuke Nakayama, Hideki Nomura and Kenji Kuba supported her work : simultaneous measurements of oxygen consumption and tension development in arterial smooth muscle. Carotid artery used in the experiment was kindly provided from Motonobu Ohtsuki (Nagoya Shokuniku Center). Gail Pyne continued this work in the Department of Biochemistry, Oxford and communicated some of the results in the 5th Annual Meeting of British Neurosurgery Research Group (Drymen, U. K. ).In the 75th Annual Meeting of the Japanese Physiological Society, a symposium entitled 'Magnesium on Nerve and Muscle Physiology' was held in Kanazawa (27th March 98). In the symposium Shinsuke Nakayama communicated some of the results concerning hormonal regulation of intracellular MgィイD12+ィエD1. also, Joseph Clark (investigator) and Peter Flatman (Lorraine Smith's former supervisor : Department of Physiology, Edinburgh) were invited. The titles of their communications were 'Magnesium in vascular smooth muscle contraction' and 'Ion transporters and magnesium homeostasis", respectively.